MetaCyc Pathway: benzoyl-CoA degradation III (anaerobic) in Cupriavidus basilensis FW507-4G11

Add experiment(s):


benzoyl-CoA + 2 ATP + 2 a reduced ferredoxin [iron-sulfur] cluster + 2 H2O→cyclohex-1,5-diene-1-carbonyl-CoA + 2 ADP + 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 phosphate (EC 1.3.7.8)
No genes
cyclohex-1,5-diene-1-carbonyl-CoA + a reduced electron-transfer flavoprotein→cyclohex-1-ene-1-carbonyl-CoA + an oxidized electron-transfer flavoprotein + H+ (EC 1.3.8.10)
No genes
cyclohex-1-ene-1-carbonyl-CoA + H2O→2-hydroxy-cyclohexane-1-carbonyl-CoA
RR42_RS18250
RR42_RS23710
2-hydroxy-cyclohexane-1-carbonyl-CoA + NAD+→2-ketocyclohexane-1-carbonyl-CoA + NADH + H+
RR42_RS13550
RR42_RS23690
2-ketocyclohexane-1-carbonyl-CoA + H2O→pimeloyl-CoA + H+
RR42_RS23695
Pimeloyl-CoA dehydrogenase:
pimeloyl-CoA + NAD+→2,3-didehydropimeloyl-CoA + NADH + H+ (EC 1.3.1.62)
RR42_RS05595
RR42_RS05600
RR42_RS28375
RR42_RS28380
RR42_RS29935
RR42_RS36390
RR42_RS36645
RR42_RS36650
2,3-didehydropimeloyl-CoA + H2O→3-hydroxypimeloyl-CoA
RR42_RS35270
3-hydroxypimeloyl-CoA dehydrogenase:
3-hydroxypimeloyl-CoA + NAD+→3-oxopimeloyl-CoA + NADH + H+ (EC 1.1.1.259)
No genes
3-oxopimeloyl-CoA + coenzyme A→glutaryl-CoA + acetyl-CoA
RR42_RS10260
RR42_RS31890

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information