MetaCyc Pathway: pyruvate fermentation to propanoate I in Cupriavidus basilensis FW507-4G11

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Methylmalonyl-CoA carboxytransferase:
(S)-methylmalonyl-CoA + pyruvate→oxaloacetate + propanoyl-CoA
(EC 2.1.3.1)
No genes
Malate dehydrogenase (in reverse):
oxaloacetate + NADH + H+→(S)-malate + NAD+
(EC 1.1.1.37; 1.1.1.38)
RR42_RS02230
RR42_RS14465
RR42_RS29130
Fumarate hydratase:
(S)-malate→fumarate + H2O
(EC 4.2.1.2)
RR42_RS02195
RR42_RS13905
RR42_RS27740
RR42_RS33090
RR42_RS37365
Succinate dehydrogenase (ubiquinone):
fumarate[in] + a menaquinol→succinate[in] + a menaquinone
(EC 1.3.5.1)
No genes
propanoyl-CoA + succinate→succinyl-CoA + propanoate (EC 2.8.3.27)
No genes
Methylmalonyl-CoA mutase (in reverse):
succinyl-CoA→(R)-methylmalonyl-CoA
(EC 5.4.99.2)
RR42_RS01600
Methylmalonyl-CoA epimerase:
(R)-methylmalonyl-CoA→(S)-methylmalonyl-CoA
(EC 5.1.99.1)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information