MetaCyc Pathway: L-histidine degradation VI in Cupriavidus basilensis FW507-4G11

Add experiment(s):


Histidine ammonia-lyase:
L-histidine→urocanate + ammonium (EC 4.3.1.3)
RR42_RS01710
RR42_RS14640
RR42_RS16920
Urocanate hydratase (in reverse):
urocanate + H2O→4-imidazolone-5-propanoate (EC 4.2.1.49)
RR42_RS14645
RR42_RS16915
Imidazolonepropionase:
4-imidazolone-5-propanoate + H2O→N-formimino-L-glutamate (EC 3.5.2.7)
RR42_RS16905
4-imidazolone-5-propanoate + dioxygen + H2O→hydantoin-5-propanoate + hydrogen peroxide
No genes
4-imidazolone-5-propanoate + H2O→formyl-L-isoglutamine (spontaneous)
No genes
4-imidazolone-5-propanoate + a reduced two electron carrier + dioxygen + H2O→4-oxoglutaramate + ammonium + an oxidized electron carrier + formate (spontaneous)
No genes
formyl-L-isoglutamine + H2O→L-isoglutamine + formate (spontaneous)
No genes
4-oxoglutaramate + H2O→2-oxoglutarate + ammonium (spontaneous)
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information