MetaCyc Pathway: L-histidine degradation I in Cupriavidus basilensis FW507-4G11

Add experiment(s):


Histidine ammonia-lyase:
L-histidine→urocanate + ammonium (EC 4.3.1.3)
RR42_RS01710
RR42_RS14640
RR42_RS16920
Urocanate hydratase (in reverse):
urocanate + H2O→4-imidazolone-5-propanoate (EC 4.2.1.49)
RR42_RS14645
RR42_RS16915
Imidazolonepropionase:
4-imidazolone-5-propanoate + H2O→N-formimino-L-glutamate (EC 3.5.2.7)
RR42_RS16905
Formimidoylglutamase:
N-formimino-L-glutamate + H2O→L-glutamate + formamide (EC 3.5.3.8)
RR42_RS14625
RR42_RS31730

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information