MetaCyc Pathway: heme b biosynthesis II (oxygen-independent) in Cupriavidus basilensis FW507-4G11

Uroporphyrinogen decarboxylase: uroporphyrinogen-III + 4 H+→coproporphyrinogen III + 4 CO2 (EC 4.1.1.37)

RR42_RS20135

coproporphyrinogen III + 2 S-adenosyl-L-methionine→protoporphyrinogen IX + 2 CO2 + 2 5'-deoxyadenosine + 2 L-methionine (EC 1.3.98.3)

RR42_RS20025

protoporphyrinogen IX[in] + 3 a menaquinone→protoporphyrin IX[in] + 3 a menaquinol (EC 1.3.5.3)

No genes

protoporphyrin IX + Fe2+→protoheme + 2 H+ (EC 4.98.1.1)

RR42_RS05925

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information