MetaCyc Pathway: γ-hexachlorocyclohexane degradation in Cupriavidus basilensis FW507-4G11

Add experiment(s):


γ-hexachlorocyclohexane→γ-pentachlorocyclohexene + chloride + H+
No genes
γ-pentachlorocyclohexene→(3R,6R)-1,3,4,6-tetrachlorocyclohexa-1,4-diene + chloride + H+
No genes
(3R,6R)-1,3,4,6-tetrachlorocyclohexa-1,4-diene→1,2,4-trichlorobenzene + chloride + H+ (spontaneous)
No genes
Haloalkane dehalogenase:
(3R,6R)-1,3,4,6-tetrachlorocyclohexa-1,4-diene + H2O→(1S,4R)-2,4,5-trichloro-2,5-cyclohexadiene-1-diol + chloride + H+
(EC 3.8.1.5)
RR42_RS01050
Haloalkane dehalogenase:
(1S,4R)-2,4,5-trichloro-2,5-cyclohexadiene-1-diol + H2O→(1S,4S)-2,5-dichloro-2,5-cyclohexadiene-1,4-diol + chloride + H+
(EC 3.8.1.5)
RR42_RS01050
(1S,4R)-2,4,5-trichloro-2,5-cyclohexadiene-1-diol→2,5-dichlorophenol + chloride + 2 H+ (spontaneous)
No genes
(1S,4S)-2,5-dichloro-2,5-cyclohexadiene-1,4-diol + NAD+→2,5-dichloro-p-quinol + NADH + H+
No genes
2,5-dichloro-p-quinol + 2 glutathione→chlorohydroquinone + chloride + glutathione disulfide + H+
No genes
chlorohydroquinone + dioxygen→5-chlorocarbonyl-4-hydroxy-penta-2,4-dienate + 2 H+
No genes
5-chlorocarbonyl-4-hydroxy-penta-2,4-dienate + H2O→2-maleylacetate + chloride + H+ (spontaneous)
No genes
Maleylacetate reductase (in reverse):
2-maleylacetate + NAD(P)H + H+→3-oxoadipate + NAD(P)+
(EC 1.3.1.32)
RR42_RS32920
RR42_RS34620

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information