MetaCyc Pathway: catechol degradation to β-ketoadipate in Cupriavidus basilensis FW507-4G11

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Catechol 1,2-dioxygenase:
catechol + dioxygen→cis,cis-muconate + 2 H+ (EC 1.13.11.1)
RR42_RS23505
RR42_RS32875
RR42_RS32880
Muconate cycloisomerase (in reverse):
cis,cis-muconate + H+→(+)-muconolactone (EC 5.5.1.1)
RR42_RS21835
Muconolactone Delta-isomerase:
(+)-muconolactone→(4,5-dihydro-5-oxofuran-2-yl)-acetate (EC 5.3.3.4)
RR42_RS10025
RR42_RS10695
RR42_RS21840
RR42_RS33065
3-oxoadipate enol-lactonase:
(4,5-dihydro-5-oxofuran-2-yl)-acetate + H2O→3-oxoadipate + H+ (EC 3.1.1.24)
RR42_RS00755
RR42_RS10565
RR42_RS10690
RR42_RS21850
RR42_RS24710
RR42_RS30700
RR42_RS32050

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information