MetaCyc Pathway: 4-hydroxymandelate degradation in Cupriavidus basilensis FW507-4G11

Add experiment(s):


Mandelate racemase (in reverse):
(R)-4-hydroxymandelate→(S)-4-hydroxymandelate (EC 5.1.2.2)
RR42_RS23065
(S)-4-hydroxymandelate + an electron-transfer quinone→4-hydroxyphenylglyoxylate + an electron-transfer quinol
No genes
Benzoylformate decarboxylase:
4-hydroxyphenylglyoxylate + H+→4-hydroxybenzaldehyde + CO2 (EC 4.1.1.7)
RR42_RS32970
4-hydroxybenzaldehyde dehydrogenase:
4-hydroxybenzaldehyde + NAD+ + H2O→4-hydroxybenzoate + NADH + 2 H+ (EC 1.2.1.64)
No genes
4-hydroxybenzaldehyde + NADP+ + H2O→4-hydroxybenzoate + NADPH + 2 H+ (EC 1.2.1.96)
No genes
4-hydroxybenzoate 3-monooxygenase:
4-hydroxybenzoate + NADPH + dioxygen + H+→protocatechuate + NADP+ + H2O (EC 1.14.13.2)
RR42_RS21940

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information