MetaCyc Pathway: 1,2-dichloroethane degradation in Cupriavidus basilensis FW507-4G11

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Haloalkane dehalogenase:
1,2-dichloroethane + H2O→2-chloroethanol + chloride + H+
(EC 3.8.1.5)
RR42_RS01050
2-chloroethanol + 2 an oxidized cytochrome cL→chloroacetaldehyde + 2 a reduced cytochrome cL + 2 H+ (EC 1.1.2.7)
No genes
Aldehyde dehydrogenase (NADP(+)):
chloroacetaldehyde + NAD+ + H2O→2-chloroacetate + NADH + 2 H+
(EC 1.2.1.4)
RR42_RS04830
RR42_RS23090
Haloacetate dehalogenase:
2-chloroacetate + H2O→glycolate + chloride + H+
(EC 3.8.1.3)
RR42_RS01050
RR42_RS01540

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information