MetaCyc Pathway: β-carotene biosynthesis (engineered) in Cupriavidus basilensis FW507-4G11

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Reactions and Genes R2A with Vancomycin 0.5 mg/ml
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2 geranylgeranyl diphosphate→prephytoene diphosphate + diphosphate (EC 2.5.1.148; 2.5.1.32)
RR42_RS07905 -0.2
RR42_RS26935 -0.1
RR42_RS32265 +1.5
Phytoene synthase:
prephytoene diphosphate→15-cis-phytoene + diphosphate (EC 2.5.1.32)
RR42_RS07905 -0.2
RR42_RS26935 -0.1
RR42_RS32265 +1.5
15-cis-phytoene + an oxidized electron carrier→all-trans phytofluene + a reduced two electron carrier (EC 1.3.99.28; 1.3.99.29; 1.3.99.30; 1.3.99.31)
No genes
all-trans phytofluene + an oxidized electron carrier→all-trans-ζ-carotene + a reduced two electron carrier (EC 1.3.99.28; 1.3.99.29; 1.3.99.30; 1.3.99.31)
No genes
all-trans-ζ-carotene + an oxidized electron carrier→all-trans neurosporene + a reduced two electron carrier (EC 1.3.99.26; 1.3.99.28; 1.3.99.30; 1.3.99.31)
No genes
all-trans neurosporene + an oxidized electron carrier→all-trans-lycopene + a reduced two electron carrier (EC 1.3.99.26; 1.3.99.30; 1.3.99.31)
No genes
all-trans-lycopene→γ-carotene (EC 5.5.1.19)
No genes
γ-carotene→β-carotene (EC 5.5.1.19)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information