MetaCyc Pathway: TCA cycle VIII (Chlamydia) in Cupriavidus basilensis FW507-4G11

Reactions and Genes	LB
2-oxoglutarate + coenzyme A + NAD+→succinyl-CoA + CO2 + NADH (EC 1.2.1.105)
RR42_RS07380	-0.9
Succinate--CoA ligase (ADP-forming) (in reverse): succinyl-CoA + ADP + phosphate→succinate + ATP + coenzyme A (EC 6.2.1.5)
RR42_RS03095	-3.2
RR42_RS03100	N.D.
RR42_RS31375	-0.4
RR42_RS31380	-0.2
Succinate dehydrogenase (ubiquinone): succinate[in] + an electron-transfer quinone→fumarate[in] + an electron-transfer quinol (EC 1.3.5.1)
RR42_RS14445	N.D.
RR42_RS14455	N.D.
Fumarate hydratase (in reverse): fumarate + H2O→(S)-malate (EC 4.2.1.2)
RR42_RS02195	-0.1
RR42_RS13905	-3.3
RR42_RS27740	+0.3
RR42_RS33090	+2.6
RR42_RS37365	+0.2
Malate dehydrogenase: (S)-malate + NAD+→oxaloacetate + NADH + H+ (EC 1.1.1.37; 1.1.1.38)
RR42_RS02230	-0.1
RR42_RS14465	N.D.
RR42_RS29130	+0.1
Aspartate transaminase (in reverse): oxaloacetate + L-glutamate→2-oxoglutarate + L-aspartate (EC 2.6.1.1)
RR42_RS01570	+0.3
RR42_RS01590	-0.3
RR42_RS02275	-0.0
RR42_RS04985	+0.4
RR42_RS05770	+0.2
RR42_RS09190	+0.1
RR42_RS09965	-0.4
RR42_RS10785	+0.1
RR42_RS12545	-0.0
RR42_RS14560	-0.1
RR42_RS15580	-0.1
RR42_RS16470	+0.5
RR42_RS21340	-0.2
RR42_RS25980	+0.4
RR42_RS26005	-0.1
RR42_RS26015	+0.0
RR42_RS26185	-0.1
RR42_RS26625	-0.0
RR42_RS28185	-0.8
RR42_RS32165	-0.4
RR42_RS33140	-0.3
RR42_RS33805	-0.5
RR42_RS35305	-0.7
RR42_RS36780	-0.3

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information