MetaCyc Pathway: L-tryptophan degradation I (via anthranilate) in Cupriavidus basilensis FW507-4G11

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Reactions and Genes L-Tryptophan (N)
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Tryptophan 2,3-dioxygenase:
L-tryptophan + dioxygen→N-formyl-L-kynurenine (EC 1.13.11.11; 1.13.11.52)
RR42_RS15390 -3.4
Arylformamidase:
N-formyl-L-kynurenine + H2O→L-kynurenine + formate + H+ (EC 3.5.1.9)
RR42_RS15380 -2.8
RR42_RS33590 +0.1
Kynureninase:
L-kynurenine + H2O→anthranilate + L-alanine + H+ (EC 3.7.1.3)
RR42_RS15385 -4.3

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information