MetaCyc Pathway: L-tyrosine degradation IV (to 4-methylphenol) in Cupriavidus basilensis FW507-4G11

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Reactions and Genes L-Phenylalanine (N)
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Aspartate transaminase:
L-tyrosine + 2-oxoglutarate→3-(4-hydroxyphenyl)pyruvate + L-glutamate (EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)
RR42_RS01570 +0.1
RR42_RS01590 -0.1
RR42_RS02275 +0.0
RR42_RS04465 -0.0
RR42_RS04985 -0.0
RR42_RS05770 -0.1
RR42_RS05990 +0.2
RR42_RS09190 +0.1
RR42_RS09965 +0.1
RR42_RS10785 -0.1
RR42_RS12545 -0.4
RR42_RS14560 +0.1
RR42_RS15580 +0.2
RR42_RS16470 -0.1
RR42_RS18910 N.D.
RR42_RS21340 -0.2
RR42_RS25980 -0.2
RR42_RS26005 +0.2
RR42_RS26015 +0.0
RR42_RS26185 -0.0
RR42_RS26625 -0.3
RR42_RS28185 +0.1
RR42_RS32165 +0.1
RR42_RS33140 -0.0
RR42_RS33490 -3.2
RR42_RS33805 -0.4
RR42_RS35305 -0.2
RR42_RS36780 -0.0
4-hydroxyphenylpyruvate oxidase:
2 3-(4-hydroxyphenyl)pyruvate + dioxygen→2 (4-hydroxyphenyl)acetate + 2 CO2 (EC 1.2.3.13)
No genes
4-hydroxyphenylacetate decarboxylase:
(4-hydroxyphenyl)acetate + H+→4-methylphenol + CO2 (EC 4.1.1.83)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information