| Reactions and Genes | L-Valine (N) |
|---|
| remove |
| arachidonoyl-CoA + malonyl-CoA + H+→(7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA + CO2 + coenzyme A |
| No genes |
| (7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA + NADPH + H+→(3R,7Z,10Z,13Z,16Z)-3-hydroxydocosatetraenoyl-CoA + NADP+ (EC 1.1.1.330) |
| No genes |
| (3R,7Z,10Z,13Z,16Z)-3-hydroxydocosatetraenoyl-CoA→(2E,7Z,10Z,13Z,16Z)-docosa-2,7,10,13,16-pentaenoyl-CoA + H2O (EC 4.2.1.134) |
| No genes |
| (2E,7Z,10Z,13Z,16Z)-docosa-2,7,10,13,16-pentaenoyl-CoA + NADPH + H+→adrenoyl-CoA + NADP+ (EC 1.3.1.93) |
| No genes |
| adrenoyl-CoA + malonyl-CoA + H+→(9Z,12Z,15Z,18Z)-3-oxotetracosatetraenoyl-CoA + CO2 + coenzyme A |
| No genes |
| (9Z,12Z,15Z,18Z)-3-oxotetracosatetraenoyl-CoA + NADPH + H+→(3R,9Z,12Z,15Z,18Z)-3-hydroxytetracosatetraenoyl-CoA + NADP+ (EC 1.1.1.330) |
| No genes |
| (3R,9Z,12Z,15Z,18Z)-3-hydroxytetracosatetraenoyl-CoA→(2E,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA + H2O (EC 4.2.1.134) |
| No genes |
| (2E,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA + NADPH + H+→(9Z,12Z,15Z,18Z)-tetracosatetraenoyl-CoA + NADP+ (EC 1.3.1.93) |
| No genes |
Linoleoyl-CoA desaturase:
(9Z,12Z,15Z,18Z)-tetracosatetraenoyl-CoA + 2 a ferrocytochrome b5 + dioxygen + 2 H+→(6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA + 2 a ferricytochrome b5 + 2 H2O (EC 1.14.19.3) |
| No genes |
Acyl-CoA oxidase:
(6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA + dioxygen→(2E,6Z,9Z,12Z,15Z,18Z)-tetracosahexaenoyl-CoA + hydrogen peroxide (EC 1.3.3.6) |
| No genes |
Enoyl-CoA hydratase (in reverse):
(2E,6Z,9Z,12Z,15Z,18Z)-tetracosahexaenoyl-CoA + H2O→(3S,6Z,9Z,12Z,15Z,18Z)-3-hydroxytetracosapentaenoyl-CoA (EC 4.2.1.17) |
| RR42_RS00730 | -0.0 |
| RR42_RS02510 | +0.1 |
| RR42_RS02525 | +0.1 |
| RR42_RS03015 | +0.2 |
| RR42_RS04550 | +0.1 |
| RR42_RS05755 | +0.3 |
| RR42_RS05760 | +0.1 |
| RR42_RS07510 | +0.2 |
| RR42_RS10250 | -0.4 |
| RR42_RS10265 | +0.2 |
| RR42_RS10270 | -0.7 |
| RR42_RS11095 | -0.1 |
| RR42_RS12500 | +0.0 |
| RR42_RS12795 | +0.1 |
| RR42_RS13545 | N.D. |
| RR42_RS16175 | +0.4 |
| RR42_RS16790 | +0.2 |
| RR42_RS18250 | -0.1 |
| RR42_RS18255 | -0.4 |
| RR42_RS19805 | -0.6 |
| RR42_RS19815 | N.D. |
| RR42_RS22630 | -0.1 |
| RR42_RS22680 | +0.2 |
| RR42_RS23295 | +0.1 |
| RR42_RS23450 | +0.1 |
| RR42_RS23710 | -0.4 |
| RR42_RS24355 | -0.1 |
| RR42_RS24895 | -0.4 |
| RR42_RS25480 | -0.2 |
| RR42_RS25525 | -0.1 |
| RR42_RS25900 | +0.0 |
| RR42_RS28050 | N.D. |
| RR42_RS28325 | +0.1 |
| RR42_RS28330 | -0.5 |
| RR42_RS28425 | +0.5 |
| RR42_RS28545 | -2.0 |
| RR42_RS28550 | -0.8 |
| RR42_RS29425 | +0.6 |
| RR42_RS29465 | +0.0 |
| RR42_RS29940 | -0.1 |
| RR42_RS29945 | -0.3 |
| RR42_RS31580 | +0.1 |
| RR42_RS31675 | -0.5 |
| RR42_RS31935 | +0.3 |
| RR42_RS31945 | -0.1 |
| RR42_RS34175 | +0.4 |
| RR42_RS34180 | -0.1 |
| RR42_RS34905 | -0.8 |
| RR42_RS35130 | -0.3 |
| RR42_RS35270 | -0.1 |
| RR42_RS36335 | +0.1 |
| RR42_RS36495 | +0.2 |
| (3S,6Z,9Z,12Z,15Z,18Z)-3-hydroxytetracosapentaenoyl-CoA + NAD+→(6Z,9Z,12Z,15Z,18Z)-3-oxotetracosapentaenoyl-CoA + NADH + H+ |
| No genes |
Acetyl-CoA C-acyltransferase (in reverse):
(6Z,9Z,12Z,15Z,18Z)-3-oxotetracosapentaenoyl-CoA + coenzyme A→(4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA + acetyl-CoA (EC 2.3.1.16) |
| RR42_RS00885 | -0.2 |
| RR42_RS02515 | N.D. |
| RR42_RS03010 | -0.2 |
| RR42_RS07610 | -0.1 |
| RR42_RS07645 | N.D. |
| RR42_RS10260 | -0.1 |
| RR42_RS10540 | +0.2 |
| RR42_RS11085 | -0.3 |
| RR42_RS16595 | +0.1 |
| RR42_RS22625 | -0.3 |
| RR42_RS24300 | +0.0 |
| RR42_RS24970 | +0.2 |
| RR42_RS25210 | +0.2 |
| RR42_RS25380 | -0.2 |
| RR42_RS25455 | -0.5 |
| RR42_RS26090 | +0.0 |
| RR42_RS27160 | -0.4 |
| RR42_RS28055 | +0.1 |
| RR42_RS31890 | -0.1 |
| RR42_RS31920 | -0.2 |
| RR42_RS35915 | +0.1 |
| RR42_RS36320 | -0.5 |
| RR42_RS37020 | -0.2 |
Links:
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information