| Reactions and Genes | L-Valine (N) |
|---|
| remove |
| a 2,3,4-saturated fatty acid + ATP + coenzyme A→a 2,3,4-saturated fatty acyl CoA + AMP + diphosphate |
| No genes |
Acyl-CoA oxidase:
a 2,3,4-saturated fatty acyl CoA + dioxygen→a (2E)-2-enoyl-CoA + hydrogen peroxide (EC 1.3.3.6) |
| No genes |
Enoyl-CoA hydratase (in reverse):
a (2E)-2-enoyl-CoA + H2O→a 2,3,4-saturated (3S)-3-hydroxyacyl-CoA (EC 4.2.1.17) |
| RR42_RS00730 | -0.0 |
| RR42_RS02510 | +0.1 |
| RR42_RS02525 | +0.1 |
| RR42_RS03015 | +0.2 |
| RR42_RS04550 | +0.1 |
| RR42_RS05755 | +0.3 |
| RR42_RS05760 | +0.1 |
| RR42_RS07510 | +0.2 |
| RR42_RS10250 | -0.4 |
| RR42_RS10265 | +0.2 |
| RR42_RS10270 | -0.7 |
| RR42_RS11095 | -0.1 |
| RR42_RS12500 | +0.0 |
| RR42_RS12795 | +0.1 |
| RR42_RS13545 | N.D. |
| RR42_RS16175 | +0.4 |
| RR42_RS16790 | +0.2 |
| RR42_RS18250 | -0.1 |
| RR42_RS18255 | -0.4 |
| RR42_RS19805 | -0.6 |
| RR42_RS19815 | N.D. |
| RR42_RS22630 | -0.1 |
| RR42_RS22680 | +0.2 |
| RR42_RS23295 | +0.1 |
| RR42_RS23450 | +0.1 |
| RR42_RS23710 | -0.4 |
| RR42_RS24355 | -0.1 |
| RR42_RS24895 | -0.4 |
| RR42_RS25480 | -0.2 |
| RR42_RS25525 | -0.1 |
| RR42_RS25900 | +0.0 |
| RR42_RS28050 | N.D. |
| RR42_RS28325 | +0.1 |
| RR42_RS28330 | -0.5 |
| RR42_RS28425 | +0.5 |
| RR42_RS28545 | -2.0 |
| RR42_RS28550 | -0.8 |
| RR42_RS29425 | +0.6 |
| RR42_RS29465 | +0.0 |
| RR42_RS29940 | -0.1 |
| RR42_RS29945 | -0.3 |
| RR42_RS31580 | +0.1 |
| RR42_RS31675 | -0.5 |
| RR42_RS31935 | +0.3 |
| RR42_RS31945 | -0.1 |
| RR42_RS34175 | +0.4 |
| RR42_RS34180 | -0.1 |
| RR42_RS34905 | -0.8 |
| RR42_RS35130 | -0.3 |
| RR42_RS35270 | -0.1 |
| RR42_RS36335 | +0.1 |
| RR42_RS36495 | +0.2 |
3-hydroxyacyl-CoA dehydrogenase:
a 2,3,4-saturated (3S)-3-hydroxyacyl-CoA + NAD+→a 2,3,4-saturated 3-oxoacyl-CoA + NADH + H+ (EC 1.1.1.35) |
| RR42_RS02510 | +0.1 |
| RR42_RS03005 | +0.2 |
| RR42_RS03440 | -0.4 |
| RR42_RS05760 | +0.1 |
| RR42_RS10265 | +0.2 |
| RR42_RS11095 | -0.1 |
| RR42_RS22630 | -0.1 |
| RR42_RS25375 | +0.1 |
| RR42_RS28325 | +0.1 |
| RR42_RS29465 | +0.0 |
| RR42_RS31050 | +0.2 |
| RR42_RS35270 | -0.1 |
Acetyl-CoA C-acyltransferase (in reverse):
a 2,3,4-saturated 3-oxoacyl-CoA + coenzyme A→a 2,3,4-saturated fatty acyl CoA + acetyl-CoA (EC 2.3.1.16) |
| RR42_RS00885 | -0.2 |
| RR42_RS02515 | N.D. |
| RR42_RS03010 | -0.2 |
| RR42_RS07610 | -0.1 |
| RR42_RS07645 | N.D. |
| RR42_RS10260 | -0.1 |
| RR42_RS10540 | +0.2 |
| RR42_RS11085 | -0.3 |
| RR42_RS16595 | +0.1 |
| RR42_RS22625 | -0.3 |
| RR42_RS24300 | +0.0 |
| RR42_RS24970 | +0.2 |
| RR42_RS25210 | +0.2 |
| RR42_RS25380 | -0.2 |
| RR42_RS25455 | -0.5 |
| RR42_RS26090 | +0.0 |
| RR42_RS27160 | -0.4 |
| RR42_RS28055 | +0.1 |
| RR42_RS31890 | -0.1 |
| RR42_RS31920 | -0.2 |
| RR42_RS35915 | +0.1 |
| RR42_RS36320 | -0.5 |
| RR42_RS37020 | -0.2 |
Citrate (Si)-synthase:
acetyl-CoA + oxaloacetate + H2O→citrate + coenzyme A + H+ (EC 2.3.3.1; 2.3.3.16; 2.3.3.3) |
| RR42_RS09325 | -0.5 |
| RR42_RS10505 | -0.6 |
| RR42_RS14430 | N.D. |
| RR42_RS32385 | -0.2 |
| RR42_RS36245 | +0.8 |
Aconitate hydratase:
citrate→cis-aconitate + H2O (EC 4.2.1.3) |
| RR42_RS11270 | -1.8 |
| RR42_RS14490 | -0.1 |
| RR42_RS23515 | -0.4 |
Aconitate hydratase:
cis-aconitate + H2O→D-threo-isocitrate (EC 4.2.1.3) |
| RR42_RS11270 | -1.8 |
| RR42_RS14490 | -0.1 |
| RR42_RS23515 | -0.4 |
Isocitrate lyase:
D-threo-isocitrate→glyoxylate + succinate (EC 4.1.3.1) |
| RR42_RS12200 | +0.1 |
| RR42_RS22175 | -0.2 |
| RR42_RS25845 | +0.1 |
Malate synthase:
acetyl-CoA + glyoxylate + H2O→(S)-malate + coenzyme A + H+ (EC 2.3.3.9) |
| RR42_RS12175 | -0.6 |
Succinate dehydrogenase (ubiquinone):
succinate[in] + an electron-transfer quinone→fumarate[in] + an electron-transfer quinol (EC 1.3.5.1) |
| RR42_RS14445 | N.D. |
| RR42_RS14455 | N.D. |
Fumarate hydratase (in reverse):
fumarate + H2O→(S)-malate (EC 4.2.1.2) |
| RR42_RS02195 | -0.2 |
| RR42_RS13905 | -0.5 |
| RR42_RS27740 | -0.2 |
| RR42_RS33090 | -0.0 |
| RR42_RS37365 | -0.2 |
Malate dehydrogenase:
(S)-malate + NAD+→oxaloacetate + NADH + H+ (EC 1.1.1.37; 1.1.1.38) |
| RR42_RS02230 | -0.1 |
| RR42_RS14465 | N.D. |
| RR42_RS29130 | -0.1 |
Phosphoenolpyruvate carboxykinase (ATP):
oxaloacetate + ATP→phosphoenolpyruvate + ADP + CO2 (EC 4.1.1.49) |
| No genes |
Links:
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information