MetaCyc Pathway: fatty acid β-oxidation IV (unsaturated, even number) in Cupriavidus basilensis FW507-4G11

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Reactions and Genes L-Valine (N)
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3-hydroxybutyryl-CoA epimerase:
a 2,3,4-saturated (3R)-3-hydroxyacyl-CoA→a 2,3,4-saturated (3S)-3-hydroxyacyl-CoA
(EC 5.1.2.3)
RR42_RS10265 +0.2
RR42_RS11095 -0.1
RR42_RS22630 -0.1
RR42_RS28325 +0.1
RR42_RS29465 +0.0
RR42_RS35270 -0.1
a (2E,4Z)-2,4-dienoyl-CoA + NADPH + H+→a (3E)-3-enoyl-CoA + NADP+ (EC 1.3.1.124)
No genes
a 2,3,4-saturated (3R)-3-hydroxyacyl-CoA→a (2E)-2-enoyl-CoA + H2O (EC 4.2.1.119)
No genes
Dodecenoyl-CoA isomerase:
a (3E)-3-enoyl-CoA→a (2E)-2-enoyl-CoA
(EC 5.3.3.8)
RR42_RS02510 +0.1
RR42_RS10265 +0.2
RR42_RS11095 -0.1
RR42_RS22630 -0.1
RR42_RS28325 +0.1
RR42_RS29465 +0.0
RR42_RS35270 -0.1
Enoyl-CoA hydratase (in reverse):
a (2E)-2-enoyl-CoA + H2O→a 2,3,4-saturated (3S)-3-hydroxyacyl-CoA
(EC 4.2.1.17)
RR42_RS00730 -0.0
RR42_RS02510 +0.1
RR42_RS02525 +0.1
RR42_RS03015 +0.2
RR42_RS04550 +0.1
RR42_RS05755 +0.3
RR42_RS05760 +0.1
RR42_RS07510 +0.2
RR42_RS10250 -0.4
RR42_RS10265 +0.2
RR42_RS10270 -0.7
RR42_RS11095 -0.1
RR42_RS12500 +0.0
RR42_RS12795 +0.1
RR42_RS13545 N.D.
RR42_RS16175 +0.4
RR42_RS16790 +0.2
RR42_RS18250 -0.1
RR42_RS18255 -0.4
RR42_RS19805 -0.6
RR42_RS19815 N.D.
RR42_RS22630 -0.1
RR42_RS22680 +0.2
RR42_RS23295 +0.1
RR42_RS23450 +0.1
RR42_RS23710 -0.4
RR42_RS24355 -0.1
RR42_RS24895 -0.4
RR42_RS25480 -0.2
RR42_RS25525 -0.1
RR42_RS25900 +0.0
RR42_RS28050 N.D.
RR42_RS28325 +0.1
RR42_RS28330 -0.5
RR42_RS28425 +0.5
RR42_RS28545 -2.0
RR42_RS28550 -0.8
RR42_RS29425 +0.6
RR42_RS29465 +0.0
RR42_RS29940 -0.1
RR42_RS29945 -0.3
RR42_RS31580 +0.1
RR42_RS31675 -0.5
RR42_RS31935 +0.3
RR42_RS31945 -0.1
RR42_RS34175 +0.4
RR42_RS34180 -0.1
RR42_RS34905 -0.8
RR42_RS35130 -0.3
RR42_RS35270 -0.1
RR42_RS36335 +0.1
RR42_RS36495 +0.2

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information