MetaCyc Pathway: β-alanine biosynthesis II in Cupriavidus basilensis FW507-4G11

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Reactions and Genes L-Valine (N)
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Propionate--CoA ligase:
propanoate + ATP + coenzyme A→propanoyl-CoA + AMP + diphosphate (EC 6.2.1.17)
RR42_RS13560 -0.0
RR42_RS13880 -0.1
propanoyl-CoA + an oxidized electron-transfer flavoprotein + H+→acryloyl-CoA + a reduced electron-transfer flavoprotein (EC 1.3.8.1)
RR42_RS00895 -0.1
RR42_RS04580 -0.0
RR42_RS11075 +0.1
RR42_RS25105 -0.4
RR42_RS28565 -0.9
RR42_RS36390 +0.0
acryloyl-CoA + H2O→3-hydroxypropanoyl-CoA (EC 4.2.1.116)
No genes
3-hydroxyisobutyryl-CoA hydrolase:
3-hydroxypropanoyl-CoA + H2O→3-hydroxypropanoate + coenzyme A + H+ (EC 3.1.2.4)
RR42_RS28545 -2.0
3-hydroxypropionate dehydrogenase:
3-hydroxypropanoate + NAD+→3-oxopropanoate + NADH + H+ (EC 1.1.1.59)
RR42_RS20290 +0.2
Beta-alanine--pyruvate transaminase:
3-oxopropanoate + L-alanine→β-alanine + pyruvate (EC 2.6.1.18)
RR42_RS01575 -0.1

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information