MetaCyc Pathway: glycine biosynthesis II in Cupriavidus basilensis FW507-4G11

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Reactions and Genes L-Serine (N)
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a [glycine-cleavage complex H protein] N6-aminomethyldihydrolipoyl-L-lysine + CO2→glycine + a [glycine-cleavage complex H protein] N6-[(R)-lipoyl]-L-lysine + H+ (EC 1.4.1.27; 1.4.4.2)
RR42_RS20070 -1.3
a [glycine-cleavage complex H protein] N6-[(R)-lipoyl]-L-lysine + NADH + H+→a [glycine-cleavage complex H protein] N6-dihydrolipoyl-L-lysine + NAD+ (EC 1.4.1.27; 1.8.1.4)
RR42_RS07380 -0.0
RR42_RS12930 N.D.
RR42_RS21770 +0.0
RR42_RS26115 -0.5
RR42_RS34380 -0.0
a [glycine-cleavage complex H protein] N6-dihydrolipoyl-L-lysine + ammonium + a 5,10-methylenetetrahydrofolate→a [glycine-cleavage complex H protein] N6-aminomethyldihydrolipoyl-L-lysine + a tetrahydrofolate (EC 1.4.1.27; 2.1.2.10)
RR42_RS20060 -1.4
RR42_RS20065 +0.8

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information