MetaCyc Pathway: L-histidine degradation II in Cupriavidus basilensis FW507-4G11

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Reactions and Genes L-Histidine (C)
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Histidine ammonia-lyase:
L-histidine→urocanate + ammonium (EC 4.3.1.3)
RR42_RS01710 +0.0
RR42_RS14640 +2.5
RR42_RS16920 -1.6
Urocanate hydratase (in reverse):
urocanate + H2O→4-imidazolone-5-propanoate (EC 4.2.1.49)
RR42_RS14645 +1.5
RR42_RS16915 -1.1
Imidazolonepropionase:
4-imidazolone-5-propanoate + H2O→N-formimino-L-glutamate (EC 3.5.2.7)
RR42_RS16905 -3.1
Formimidoylglutamate deiminase:
N-formimino-L-glutamate + H2O→N-formyl-L-glutamate + ammonium (EC 3.5.3.13)
RR42_RS16900 -0.0
N-formylglutamate deformylase:
N-formyl-L-glutamate + H2O→L-glutamate + formate (EC 3.5.1.68)
RR42_RS05795 +0.1
RR42_RS15355 +0.0
RR42_RS16895 -2.4
RR42_RS20220 -0.2

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information