MetaCyc Pathway: superpathway of L-serine and glycine biosynthesis I in Cupriavidus basilensis FW507-4G11

Add experiment(s):


Reactions and Genes Trisodium citrate (C)
remove
Phosphoglycerate dehydrogenase:
3-phospho-D-glycerate + NAD+→3-phosphooxypyruvate + NADH + H+ (EC 1.1.1.95)
RR42_RS00950 +0.3
RR42_RS02235 +0.6
RR42_RS03865 +0.2
RR42_RS05155 -0.1
RR42_RS10510 +0.1
RR42_RS10615 +0.0
RR42_RS10620 +0.1
RR42_RS20535 -0.3
RR42_RS26540 +0.5
RR42_RS27010 -1.6
RR42_RS27410 -0.6
RR42_RS33330 +0.2
RR42_RS33660 +0.1
RR42_RS34610 -0.5
RR42_RS37380 -0.3
Phosphoserine transaminase (in reverse):
3-phosphooxypyruvate + L-glutamate→O-phospho-L-serine + 2-oxoglutarate (EC 2.6.1.52)
RR42_RS04455 N.D.
Phosphoserine phosphatase:
O-phospho-L-serine + H2O→L-serine + phosphate (EC 3.1.3.3)
RR42_RS07660 N.D.
RR42_RS17230 -0.3
RR42_RS21330 +0.3
RR42_RS28245 +0.3
Glycine hydroxymethyltransferase:
L-serine + a tetrahydrofolate→glycine + a 5,10-methylenetetrahydrofolate + H2O (EC 2.1.2.1)
RR42_RS15485 N.D.

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information