MetaCyc Pathway: fatty acid biosynthesis initiation (mitochondria) in Cupriavidus basilensis FW507-4G11

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Reactions and Genes R2A with Doxycycline hyclate 0.0001 mg/ml
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[Acyl-carrier-protein] S-acetyltransferase:
acetyl-CoA + a soluble [acyl-carrier protein]→an acetyl-[acp] + coenzyme A (EC 2.3.1.38)
No genes
malonate + ATP + coenzyme A→malonyl-CoA + AMP + diphosphate (EC 6.2.1.76)
No genes
[Acyl-carrier-protein] S-malonyltransferase:
malonyl-CoA + a soluble [acyl-carrier protein]→a malonyl-[acp] + coenzyme A (EC 2.3.1.39)
RR42_RS02935 +0.1
RR42_RS14105 N.D.
Beta-ketoacyl-acyl-carrier-protein synthase II:
an acetyl-[acp] + a malonyl-[acp] + H+→an acetoacetyl-[acp] + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.179; 2.3.1.41)
RR42_RS14090 N.D.
RR42_RS31185 +2.0
RR42_RS31200 +0.4

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information