MetaCyc Pathway: fatty acid elongation -- saturated in Cupriavidus basilensis FW507-4G11

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Reactions and Genes R2A with Doxycycline hyclate 0.0001 mg/ml
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Beta-ketoacyl-acyl-carrier-protein synthase II:
a 2,3,4-saturated fatty acyl-[acp] + a malonyl-[acp] + H+→a 3-oxoacyl-[acyl-carrier protein] + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.179; 2.3.1.41)
RR42_RS14090 N.D.
RR42_RS31185 +2.0
RR42_RS31200 +0.4
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
a 3-oxoacyl-[acyl-carrier protein] + NADPH + H+→a (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ (EC 1.1.1.100)
RR42_RS04765 -0.2
RR42_RS08710 +0.1
RR42_RS09330 -0.2
RR42_RS10255 +0.2
RR42_RS10315 +0.1
RR42_RS10320 -0.1
RR42_RS11070 -0.4
RR42_RS11550 -0.9
RR42_RS13675 -0.5
RR42_RS13690 +0.1
RR42_RS14100 N.D.
RR42_RS16365 +0.0
RR42_RS16375 +0.1
RR42_RS16800 +0.2
RR42_RS17660 +0.3
RR42_RS21765 -0.2
RR42_RS21790 -0.7
RR42_RS21865 -0.0
RR42_RS22390 +0.3
RR42_RS22710 -1.0
RR42_RS22740 +0.3
RR42_RS22810 -0.3
RR42_RS23420 +0.4
RR42_RS23690 +0.7
RR42_RS24195 -0.1
RR42_RS25125 +0.3
RR42_RS25495 -0.1
RR42_RS28045 -0.6
RR42_RS28985 +0.2
RR42_RS29305 -0.0
RR42_RS31190 +0.3
RR42_RS31670 -0.2
RR42_RS31820 -0.2
RR42_RS31835 +0.0
RR42_RS31900 -1.6
RR42_RS33070 +0.3
RR42_RS33710 +0.1
RR42_RS34680 -0.1
RR42_RS35910 -0.2
RR42_RS36415 -0.1
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R)-3-hydroxyacyl-[acyl-carrier protein]→a trans-2-enoyl-[acyl-carrier protein] + H2O (EC 4.2.1.59)
RR42_RS11820 N.D.
Enoyl-[acyl-carrier-protein] reductase (NADH) (in reverse):
a trans-2-enoyl-[acyl-carrier protein] + NADH + H+→a 2,3,4-saturated fatty acyl-[acp] + NAD+ (EC 1.3.1.9)
RR42_RS03815 -0.3
RR42_RS10070 +0.0
RR42_RS10225 +0.1
RR42_RS13390 -0.0
RR42_RS25240 +0.2
RR42_RS31520 +0.3
RR42_RS31940 +0.1
RR42_RS36330 +0.0
Enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) (in reverse):
a trans-2-enoyl-[acyl-carrier protein] + NADPH + H+→a 2,3,4-saturated fatty acyl-[acp] + NADP+ (EC 1.3.1.10; 1.3.1.104; 1.3.1.39)
RR42_RS13390 -0.0
RR42_RS36330 +0.0

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information