MetaCyc Pathway: methoxylated aromatic compound degradation II in Methanococcus maripaludis S2

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Reactions and Genes McCas_H2_complete Bacitracin 0.003125 mM
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a methoxylated aromatic compound + a [Co(I) methoxylated-aromatic-compound-specific corrinoid protein] + H+→a [methyl-Co(III) methoxylated-aromatic-compound-specific corrinoid protein] + a phenol (EC 2.1.1.382)
No genes
a [methyl-Co(III) methoxylated-aromatic-compound-specific corrinoid protein] + tetrahydromethanopterin→5-methyltetrahydromethanopterin + a [Co(I) methoxylated-aromatic-compound-specific corrinoid protein] + H+ (EC 2.1.1.384)
No genes
5-methyltetrahydromethanopterin + an oxidized factor 420→5,10-methylene-tetrahydromethanopterin + a reduced factor 420 (EC 1.5.98.2)
MMP_RS00340 N.D.
5-methyltetrahydromethanopterin + CO2 + coenzyme A + 2 H+ + 2 a reduced ferredoxin [iron-sulfur] cluster→tetrahydromethanopterin + acetyl-CoA + 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O (EC 2.3.3.M4)
No genes
5,10-methylene-tetrahydromethanopterin + an oxidized factor 420 + H+→5,10-methenyltetrahydromethanopterin + a reduced factor 420 (EC 1.5.98.1)
MMP_RS01985 -0.1
Acetate--CoA ligase (ADP-forming) (in reverse):
acetyl-CoA + ADP + phosphate→acetate + ATP + coenzyme A (EC 6.2.1.13)
MMP_RS01370 -0.5
Methenyltetrahydromethanopterin cyclohydrolase:
5,10-methenyltetrahydromethanopterin + H2O→5-formyl-tetrahydromethanopterin + H+ (EC 3.5.4.27)
MMP_RS06135 N.D.
Formylmethanofuran--tetrahydromethanopterin N-formyltransferase (in reverse):
5-formyl-tetrahydromethanopterin + a methanofuran→tetrahydromethanopterin + a formylmethanofuran + H+ (EC 2.3.1.101)
MMP_RS08270 N.D.
a formylmethanofuran + 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O→CO2 + a methanofuran + H+ + 2 a reduced ferredoxin [iron-sulfur] cluster (EC 1.2.7.12)
MMP_RS02695 -1.1
MMP_RS02700 -1.6
MMP_RS02710 -0.1
MMP_RS06415 N.D.
MMP_RS06420 N.D.
MMP_RS06425 N.D.
MMP_RS08715 -2.0

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information