MetaCyc Pathway: fatty acid salvage in Cupriavidus basilensis FW507-4G11

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Reactions and Genes Carbon source Phenylacetic 2.5 mM
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Butyrate--CoA ligase:
decanoate + ATP + coenzyme A→decanoyl-CoA + AMP + diphosphate (EC 6.2.1.2; 6.2.1.3)
RR42_RS01625 +0.1
RR42_RS18150 -0.1
RR42_RS18540 -0.1
RR42_RS25195 -0.1
RR42_RS26915 +0.1
RR42_RS28980 +0.0
RR42_RS29035 +0.0
RR42_RS29460 +0.0
RR42_RS29475 -0.0
RR42_RS36095 +0.1
RR42_RS36385 +0.0
RR42_RS36505 +0.2
decanoyl-CoA + an oxidized electron-transfer flavoprotein + H+→(2E)-dec-2-enoyl-CoA + a reduced electron-transfer flavoprotein (EC 1.3.8.7)
RR42_RS01285 -0.0
RR42_RS02505 +0.2
RR42_RS10230 -0.3
RR42_RS11190 -0.0
RR42_RS21260 -0.1
RR42_RS25190 +0.0
Long-chain-enoyl-CoA hydratase (in reverse):
(2E)-dec-2-enoyl-CoA + H2O→(S)-3-hydroxydecanoyl-CoA (EC 4.2.1.74)
RR42_RS00730 +0.2
RR42_RS02510 +0.0
RR42_RS02525 -0.1
RR42_RS03015 -0.1
RR42_RS04550 -0.2
RR42_RS05755 -0.1
RR42_RS10250 -0.5
RR42_RS10265 -0.2
RR42_RS10270 +0.2
RR42_RS11095 -0.4
RR42_RS12500 -0.1
RR42_RS12795 +0.4
RR42_RS13545 N.D.
RR42_RS16175 +0.5
RR42_RS16790 -0.2
RR42_RS18250 -1.5
RR42_RS19805 -0.2
RR42_RS22630 +0.0
RR42_RS22680 -0.8
RR42_RS23295 +0.4
RR42_RS23450 +0.1
RR42_RS23710 -0.3
RR42_RS24355 -0.1
RR42_RS24895 +0.0
RR42_RS25480 +0.4
RR42_RS25525 +0.0
RR42_RS25900 -0.1
RR42_RS28050 N.D.
RR42_RS28325 +0.1
RR42_RS28330 +0.5
RR42_RS29425 -0.3
RR42_RS29465 +0.1
RR42_RS29940 -0.0
RR42_RS29945 -0.0
RR42_RS31580 +0.3
RR42_RS31935 -0.0
RR42_RS31945 -0.1
RR42_RS34175 -0.3
RR42_RS34180 +0.1
RR42_RS34905 -0.1
RR42_RS35270 +0.0
RR42_RS36495 +0.4
3-hydroxyacyl-CoA dehydrogenase:
(S)-3-hydroxydecanoyl-CoA + NAD+→3-oxodecanoyl-CoA + NADH + H+ (EC 1.1.1.35)
RR42_RS02510 +0.0
RR42_RS03005 -0.4
RR42_RS03440 -0.2
RR42_RS05760 -2.6
RR42_RS10265 -0.2
RR42_RS11095 -0.4
RR42_RS22630 +0.0
RR42_RS25375 +0.2
RR42_RS28325 +0.1
RR42_RS29465 +0.1
RR42_RS31050 -0.5
RR42_RS35270 +0.0
Acetyl-CoA C-acyltransferase (in reverse):
3-oxodecanoyl-CoA + coenzyme A→octanoyl-CoA + acetyl-CoA (EC 2.3.1.16)
RR42_RS00885 -0.4
RR42_RS02515 N.D.
RR42_RS03010 -0.1
RR42_RS07610 -0.5
RR42_RS07645 N.D.
RR42_RS10260 -0.0
RR42_RS10540 -0.5
RR42_RS11085 +0.3
RR42_RS16595 +0.1
RR42_RS22625 -0.2
RR42_RS24300 +0.1
RR42_RS24970 +0.1
RR42_RS25210 +0.0
RR42_RS25380 +0.2
RR42_RS25455 +0.1
RR42_RS26090 +0.1
RR42_RS27160 +0.3
RR42_RS28055 +0.2
RR42_RS31890 -0.3
RR42_RS31920 -0.9
RR42_RS35915 -2.0
RR42_RS36320 -0.5
RR42_RS37020 -0.1
octanoyl-CoA + a malonyl-[acp] + H+→a 3-oxodecanoyl-[acp] + CO2 + coenzyme A (EC 2.3.1.207)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information