MetaCyc Pathway: L-tryptophan degradation X (mammalian, via tryptamine) in Cupriavidus basilensis FW507-4G11

Reactions and Genes	Carbon source Phenylacetic 2.5 mM
L-tryptophan + H+→tryptamine + CO2 (EC 4.1.1.105; 4.1.1.28)
RR42_RS26695	+0.2
Monoamine oxidase: tryptamine + dioxygen + H2O→(indol-3-yl)acetaldehyde + ammonium + hydrogen peroxide (EC 1.4.3.4)
RR42_RS24620	-0.3
RR42_RS24630	-0.0
RR42_RS24640	+0.1
Indole-3-acetaldehyde reductase (NADPH) (in reverse): (indol-3-yl)acetaldehyde + NADPH + H+→(indol-3-yl)ethanol + NADP+ (EC 1.1.1.191; 1.1.1.2)
No genes
Aldehyde dehydrogenase (NAD(+)): (indol-3-yl)acetaldehyde + NAD+ + H2O→(indol-3-yl)acetate + NADH + 2 H+ (EC 1.2.1.3)
RR42_RS01275	+0.0
RR42_RS04280	-0.0
RR42_RS11360	-0.1
RR42_RS13660	+0.1
RR42_RS18500	-0.4
RR42_RS21485	+0.1
RR42_RS23750	-2.5
RR42_RS24065	-0.2
RR42_RS24390	+0.1
RR42_RS24705	+0.1
RR42_RS24840	-0.2
RR42_RS25005	+0.0
RR42_RS25010	+0.2
RR42_RS26255	-0.0
RR42_RS27350	-0.4
RR42_RS27780	+0.0
RR42_RS29955	-0.1
RR42_RS32140	-0.0
RR42_RS34255	-0.0

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information