MetaCyc Pathway: phenylacetate degradation II (anaerobic) in Cupriavidus basilensis FW507-4G11

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Reactions and Genes Carbon source Phenylacetic 2.5 mM
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Phenylacetate--CoA ligase:
phenylacetate + ATP + coenzyme A→phenylacetyl-CoA + AMP + diphosphate
(EC 6.2.1.30)
RR42_RS01655 +0.1
RR42_RS18265 +0.2
RR42_RS23755 -1.8
Phenylacetyl-CoA dehydrogenase:
phenylacetyl-CoA + 2 a quinone + H2O→phenylglyoxylyl-CoA + 2 a quinol
(EC 1.17.5.1)
No genes
Phenylacetyl-CoA hydrolase:
phenylglyoxylyl-CoA + H2O→phenylglyoxylate + coenzyme A + H+
(EC 3.1.2.25)
No genes
Phenylglyoxylate dehydrogenase (acylating):
phenylglyoxylate + coenzyme A + NAD+→benzoyl-CoA + CO2 + NADH
(EC 1.2.1.58)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information