MetaCyc Pathway: ethanol degradation II in Cupriavidus basilensis FW507-4G11

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Reactions and Genes Carbon source Phenylacetic 2.5 mM
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Alcohol dehydrogenase:
ethanol + NAD+→acetaldehyde + NADH + H+ (EC 1.1.1.1)
RR42_RS09745 -0.1
RR42_RS10210 +0.1
RR42_RS10545 -0.3
RR42_RS11005 -0.3
RR42_RS18350 -0.1
RR42_RS24070 -0.2
RR42_RS24560 +0.1
RR42_RS25355 +0.3
RR42_RS25775 N.D.
RR42_RS28650 N.D.
RR42_RS32920 -0.1
RR42_RS34260 +0.2
RR42_RS34620 -0.2
RR42_RS36940 -0.4
Aldehyde dehydrogenase (NAD(+)):
acetaldehyde + NAD+ + H2O→acetate + NADH + 2 H+ (EC 1.2.1.3)
RR42_RS01275 +0.3
RR42_RS04280 -0.1
RR42_RS11360 -0.2
RR42_RS13660 +0.1
RR42_RS18500 +0.3
RR42_RS21485 +0.1
RR42_RS23750 -2.3
RR42_RS24065 +0.1
RR42_RS24390 +0.1
RR42_RS24705 +0.3
RR42_RS24840 -0.2
RR42_RS25005 -0.3
RR42_RS25010 -0.2
RR42_RS26255 -0.1
RR42_RS27350 +0.1
RR42_RS27780 +0.1
RR42_RS29955 +0.0
RR42_RS32140 +0.0
RR42_RS34255 -0.2
Acetate--CoA ligase:
acetate + ATP + coenzyme A→acetyl-CoA + AMP + diphosphate (EC 6.2.1.1)
RR42_RS06210 +0.1
RR42_RS10650 -0.2
RR42_RS13880 -0.3
RR42_RS22715 +0.1
RR42_RS24890 -0.1
RR42_RS29035 -0.1

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information