MetaCyc Pathway: superpathway of NAD/NADP - NADH/NADPH interconversion (yeast) in Cupriavidus basilensis FW507-4G11

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Reactions and Genes Carbon source Phenylacetic 2.5 mM
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NAD(+) kinase:
NAD+ + ATP→NADP+ + ADP + H+ (EC 2.7.1.23; 2.7.1.M29)
RR42_RS05915 N.D.
Aldehyde dehydrogenase (NADP(+)):
NADP+ + an aldehyde + H2O→NADPH + a carboxylate + 2 H+ (EC 1.2.1.4)
RR42_RS04830 +0.3
RR42_RS23090 -0.0
RR42_RS27780 +0.1
Aldehyde dehydrogenase (NAD(+)):
NAD+ + an aldehyde + H2O→NADH + a carboxylate + 2 H+ (EC 1.2.1.3)
RR42_RS01275 +0.3
RR42_RS04280 -0.1
RR42_RS11360 -0.2
RR42_RS13660 +0.1
RR42_RS18500 +0.3
RR42_RS21485 +0.1
RR42_RS23750 -2.3
RR42_RS24065 +0.1
RR42_RS24390 +0.1
RR42_RS24705 +0.3
RR42_RS24840 -0.2
RR42_RS25005 -0.3
RR42_RS25010 -0.2
RR42_RS26255 -0.1
RR42_RS27350 +0.1
RR42_RS27780 +0.1
RR42_RS29955 +0.0
RR42_RS32140 +0.0
RR42_RS34255 -0.2
Glucose-6-phosphate dehydrogenase:
NADP+ + D-glucopyranose 6-phosphate→NADPH + 6-phospho D-glucono-1,5-lactone + H+ (EC 1.1.1.49)
RR42_RS03375 +0.3
RR42_RS37405 +0.1
Isocitrate dehydrogenase (NADP(+)):
NADP+ + D-threo-isocitrate→NADPH + 2-oxoglutarate + CO2 (EC 1.1.1.42)
RR42_RS17135 +0.0
RR42_RS22955 -0.1
RR42_RS28800 +0.1
RR42_RS29535 +0.0
Aldehyde dehydrogenase (NADP(+)):
NADP+ + acetaldehyde + H2O→NADPH + acetate + 2 H+ (EC 1.2.1.4)
RR42_RS04830 +0.3
RR42_RS23090 -0.0
NADH kinase:
NADH + ATP→NADPH + ADP + H+ (EC 2.7.1.86; 2.7.1.M29)
No genes
NADH[in] + H+[in] + a ubiquinone→NAD+[in] + a ubiquinol (EC 1.6.5.9)
RR42_RS12790 -0.2

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information