MetaCyc Pathway: salicylate degradation IV in Cupriavidus basilensis FW507-4G11
| Reactions and Genes | Protocatechuic Acid (C) |
|---|---|
| remove | |
| salicylate + ATP + H+→(salicyl)adenylate + diphosphate (EC 6.2.1.61; 6.2.1.65) | |
| No genes | |
| (salicyl)adenylate + coenzyme A→salicyl-CoA + AMP + H+ (EC 6.2.1.65) | |
| No genes | |
| salicyl-CoA + NADH + dioxygen + H+→gentisyl-CoA + NAD+ + H2O (EC 1.14.13.209) | |
| No genes | |
| gentisyl-CoA + H2O→gentisate + coenzyme A + H+ (spontaneous) | |
| No genes | |
| Gentisate 1,2-dioxygenase: gentisate + dioxygen→3-maleylpyruvate + H+ (EC 1.13.11.4) | |
| RR42 | -0.4 |
| RR42 | +0.3 |
| RR42 | -0.2 |
| RR42 | +0.0 |
| RR42 | +3.1 |
Links:
- Pathway details at MetaCyc
- Fitness data for 5 genes
- All MetaCyc pathways for Cupriavidus basilensis FW507-4G11
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information