MetaCyc Pathway: methylsalicylate degradation in Cupriavidus basilensis FW507-4G11

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Reactions and Genes Protocatechuic Acid (C)
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Salicylate 1-monooxygenase:
5-methylsalicylate + NADH + dioxygen + 2 H+→4-methylcatechol + CO2 + NAD+ + H2O (EC 1.14.13.1)
RR42_RS03265 +0.3
RR42_RS06410 +0.4
RR42_RS14855 +0.0
RR42_RS21625 -0.1
RR42_RS22480 -0.3
RR42_RS24050 -0.2
RR42_RS24155 -0.2
RR42_RS24285 +0.1
RR42_RS25760 -0.1
RR42_RS30505 +3.6
Salicylate 1-monooxygenase:
4-methylsalicylate + NADH + dioxygen + 2 H+→4-methylcatechol + CO2 + NAD+ + H2O (EC 1.14.13.1)
RR42_RS03265 +0.3
RR42_RS06410 +0.4
RR42_RS14855 +0.0
RR42_RS21625 -0.1
RR42_RS22480 -0.3
RR42_RS24050 -0.2
RR42_RS24155 -0.2
RR42_RS24285 +0.1
RR42_RS25760 -0.1
RR42_RS30505 +3.6

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information