Conservation of cofitness between MCAODC_27510 and MCAODC_08930 in Escherichia coli ECRC101

15 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli ECRC101 1.0 MCAODC_27510 cof HMP-PP phosphatase 1.0 MCAODC_08930 tdcE 2-ketobutyrate formate-lyase/pyruvate formate-lyase 0.59 6
Escherichia coli ECRC102 1.00 NIAGMN_06340 cof HMP-PP phosphatase 1.00 NIAGMN_16180 tdcE 2-ketobutyrate formate-lyase/pyruvate formate-lyase — —
Escherichia coli ECRC100 1.00 OKFHMN_08285 cof HMP-PP phosphatase 1.00 OKFHMN_18415 tdcE 2-ketobutyrate formate-lyase/pyruvate formate-lyase low > 80
Escherichia coli ECRC99 1.00 KEDOAH_19680 cof HMP-PP phosphatase 1.00 KEDOAH_09730 tdcE 2-ketobutyrate formate-lyase/pyruvate formate-lyase — —
Escherichia coli ECRC98 1.00 JDDGAC_11940 cof HMP-PP phosphatase 1.00 JDDGAC_22050 tdcE 2-ketobutyrate formate-lyase/pyruvate formate-lyase low > 86
Escherichia coli BL21 0.99 ECD_00398 thiamine pyrimidine pyrophosphate hydrolase; HMP-PP phosphatase 1.00 ECD_02981 pyruvate formate-lyase 4/2-ketobutyrate formate-lyase low > 61
Escherichia coli ECOR27 0.99 NOLOHH_01220 cof HMP-PP phosphatase 1.00 NOLOHH_10195 tdcE 2-ketobutyrate formate-lyase/pyruvate formate-lyase low > 75
Escherichia coli HS(pFamp)R (ATCC 700891) 0.99 OHPLBJKB_03227 HMP-PP phosphatase 1.00 OHPLBJKB_00586 PFL-like enzyme TdcE low > 73
Escherichia fergusonii Becca 0.99 EFB2_03611 HMP-PP phosphatase 0.99 EFB2_00700 PFL-like enzyme TdcE low > 86
Escherichia coli ECRC62 0.99 BNILDI_22635 cof HMP-PP phosphatase 1.00 BNILDI_01330 tdcE 2-ketobutyrate formate-lyase/pyruvate formate-lyase low > 75
Escherichia coli ECOR38 0.99 HEPCGN_06900 cof HMP-PP phosphatase 1.00 HEPCGN_17250 tdcE 2-ketobutyrate formate-lyase/pyruvate formate-lyase low > 87
Escherichia coli BW25113 0.99 b0446 cof orf, hypothetical protein (VIMSS) 1.00 b3114 tdcE pyruvate formate-lyase 4/2-ketobutyrate formate-lyase (NCBI) low > 76
Escherichia coli Nissle 1917 0.99 ECOLIN_RS02670 HMP-PP phosphatase 0.99 ECOLIN_RS17925 2-ketobutyrate formate-lyase/pyruvate formate-lyase low > 55
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.83 GFF4362 HMP-PP hydrolase (pyridoxal phosphatase) Cof, detected in genetic screen for thiamin metabolic genes (PMID:15292217) 0.94 GFF3207 2-ketobutyrate formate-lyase (EC 2.3.1.-) / Pyruvate formate-lyase (EC 2.3.1.54) low > 78
Enterobacter sp. TBS_079 0.80 MPMX20_01037 HMP-PP phosphatase 0.90 MPMX20_04018 PFL-like enzyme TdcE low > 85
Enterobacter asburiae PDN3 0.79 EX28DRAFT_2524 HAD-superfamily hydrolase, subfamily IIB 0.91 EX28DRAFT_3175 formate acetyltransferase 1 low > 76

Not shown: 5 genomes with orthologs for MCAODC_27510 only; 0 genomes with orthologs for MCAODC_08930 only