Strain Fitness in Bacteroides thetaiotaomicron VPI-5482 around BT1449

Experiment: BHIS with Dimetridazole 0.00625 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntBT1447 and BT1448 are separated by 91 nucleotidesBT1448 and BT1449 are separated by 65 nucleotidesBT1449 and BT1450 are separated by 55 nucleotides BT1447: BT1447 - two-component system sensor histidine kinase (NCBI ptt file), at 1,781,157 to 1,783,514 BT1447 BT1448: BT1448 - biotin carboxyl carrier protein (NCBI ptt file), at 1,783,606 to 1,784,130 BT1448 BT1449: BT1449 - biotin carboxylase (NCBI ptt file), at 1,784,196 to 1,785,707 BT1449 BT1450: BT1450 - propionyl-CoA carboxylase beta chain (NCBI ptt file), at 1,785,763 to 1,787,307 BT1450 Position (kb) 1784 1785 1786Strain fitness (log2 ratio) -4 -3 -2 -1 0 1 2at 1783.211 kb on - strand, within BT1447at 1783.359 kb on + strandat 1783.372 kb on + strandat 1783.372 kb on + strandat 1783.412 kb on + strandat 1783.463 kb on + strandat 1783.514 kb on + strandat 1783.529 kb on + strandat 1783.533 kb on + strandat 1783.533 kb on + strandat 1783.534 kb on - strandat 1783.541 kb on + strandat 1783.772 kb on + strand, within BT1448at 1783.773 kb on - strand, within BT1448at 1783.849 kb on - strand, within BT1448at 1783.852 kb on + strand, within BT1448at 1783.873 kb on + strand, within BT1448at 1783.874 kb on - strand, within BT1448at 1783.874 kb on - strand, within BT1448at 1784.015 kb on - strand, within BT1448at 1784.070 kb on + strand, within BT1448at 1784.070 kb on + strand, within BT1448at 1784.073 kb on - strand, within BT1448at 1784.089 kb on - strandat 1784.109 kb on - strandat 1784.124 kb on + strandat 1784.125 kb on - strandat 1784.160 kb on + strandat 1784.193 kb on + strandat 1784.204 kb on + strandat 1784.405 kb on - strand, within BT1449at 1784.481 kb on - strand, within BT1449at 1784.743 kb on + strand, within BT1449at 1784.802 kb on - strand, within BT1449at 1784.827 kb on - strand, within BT1449at 1784.827 kb on - strand, within BT1449at 1784.905 kb on + strand, within BT1449at 1785.058 kb on + strand, within BT1449at 1785.058 kb on + strand, within BT1449at 1785.106 kb on + strand, within BT1449at 1785.107 kb on - strand, within BT1449at 1785.116 kb on + strand, within BT1449at 1785.117 kb on - strand, within BT1449at 1785.248 kb on + strandat 1785.248 kb on + strand, within BT1449at 1785.256 kb on - strand, within BT1449at 1785.258 kb on + strand, within BT1449at 1785.537 kb on - strand, within BT1449at 1785.666 kb on - strandat 1785.669 kb on + strandat 1785.762 kb on - strandat 1785.881 kb on + strandat 1785.991 kb on + strand, within BT1450at 1785.997 kb on - strand, within BT1450at 1786.092 kb on - strand, within BT1450at 1786.104 kb on - strand, within BT1450at 1786.110 kb on + strand, within BT1450at 1786.176 kb on + strand, within BT1450at 1786.249 kb on + strand, within BT1450at 1786.252 kb on - strand, within BT1450at 1786.374 kb on + strand, within BT1450at 1786.447 kb on + strand, within BT1450at 1786.461 kb on + strand, within BT1450at 1786.461 kb on + strand, within BT1450at 1786.461 kb on + strand, within BT1450at 1786.561 kb on - strand, within BT1450at 1786.561 kb on - strand, within BT1450at 1786.585 kb on - strand, within BT1450at 1786.598 kb on + strand, within BT1450at 1786.599 kb on - strand, within BT1450at 1786.599 kb on - strand, within BT1450at 1786.605 kb on + strand, within BT1450

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Per-strain Table

Position Strand Gene LocusTag Fraction BHIS with Dimetridazole 0.00625 mM
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1,783,211 - BT1447 0.87 -1.3
1,783,359 + -0.3
1,783,372 + +0.7
1,783,372 + -0.5
1,783,412 + +2.7
1,783,463 + -0.9
1,783,514 + +0.1
1,783,529 + -1.3
1,783,533 + -1.3
1,783,533 + -0.3
1,783,534 - -0.3
1,783,541 + +0.7
1,783,772 + BT1448 0.32 -1.4
1,783,773 - BT1448 0.32 -0.8
1,783,849 - BT1448 0.46 -1.3
1,783,852 + BT1448 0.47 +0.7
1,783,873 + BT1448 0.51 -3.8
1,783,874 - BT1448 0.51 -2.8
1,783,874 - BT1448 0.51 -0.5
1,784,015 - BT1448 0.78 -0.3
1,784,070 + BT1448 0.88 -0.3
1,784,070 + BT1448 0.88 +0.7
1,784,073 - BT1448 0.89 -0.5
1,784,089 - -1.6
1,784,109 - +2.7
1,784,124 + -2.3
1,784,125 - -0.9
1,784,160 + -2.1
1,784,193 + +1.7
1,784,204 + -3.4
1,784,405 - BT1449 0.14 -3.1
1,784,481 - BT1449 0.19 -1.8
1,784,743 + BT1449 0.36 -2.1
1,784,802 - BT1449 0.40 -1.3
1,784,827 - BT1449 0.42 -1.3
1,784,827 - BT1449 0.42 +1.3
1,784,905 + BT1449 0.47 -1.1
1,785,058 + BT1449 0.57 -0.1
1,785,058 + BT1449 0.57 +0.2
1,785,106 + BT1449 0.60 -2.4
1,785,107 - BT1449 0.60 -0.3
1,785,116 + BT1449 0.61 -0.3
1,785,117 - BT1449 0.61 -0.3
1,785,248 + +0.7
1,785,248 + BT1449 0.70 -1.9
1,785,256 - BT1449 0.70 -0.3
1,785,258 + BT1449 0.70 -2.6
1,785,537 - BT1449 0.89 +0.1
1,785,666 - -1.3
1,785,669 + -0.3
1,785,762 - +0.7
1,785,881 + -0.3
1,785,991 + BT1450 0.15 -0.9
1,785,997 - BT1450 0.15 -1.1
1,786,092 - BT1450 0.21 -1.3
1,786,104 - BT1450 0.22 -2.5
1,786,110 + BT1450 0.22 -1.6
1,786,176 + BT1450 0.27 -1.5
1,786,249 + BT1450 0.31 -0.5
1,786,252 - BT1450 0.32 -0.6
1,786,374 + BT1450 0.40 -2.2
1,786,447 + BT1450 0.44 -1.3
1,786,461 + BT1450 0.45 -2.5
1,786,461 + BT1450 0.45 +1.3
1,786,461 + BT1450 0.45 -0.9
1,786,561 - BT1450 0.52 -2.1
1,786,561 - BT1450 0.52 -0.9
1,786,585 - BT1450 0.53 -0.9
1,786,598 + BT1450 0.54 -2.3
1,786,599 - BT1450 0.54 -0.9
1,786,599 - BT1450 0.54 -0.3
1,786,605 + BT1450 0.54 +0.7

Or see this region's nucleotide sequence