Strain Fitness in Bacteroides thetaiotaomicron VPI-5482 around BT1542

Experiment: BHIS with Thioridazine 0.025 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntBT1540 and BT1541 are separated by 88 nucleotidesBT1541 and BT1542 are separated by 103 nucleotidesBT1542 and BT1543 are separated by 565 nucleotides BT1540: BT1540 - transcriptional regulator (NCBI ptt file), at 1,899,503 to 1,900,342 BT1540 BT1541: BT1541 - conserved hypothetical protein (NCBI ptt file), at 1,900,431 to 1,901,012 BT1541 BT1542: BT1542 - putative pyridine nucleotide-disulfide oxidoreductase (NCBI ptt file), at 1,901,116 to 1,902,489 BT1542 BT1543: BT1543 - putative ABC transporter ATP-binding protein (NCBI ptt file), at 1,903,055 to 1,904,653 BT1543 Position (kb) 1901 1902 1903Strain fitness (log2 ratio) -5 -4 -3 -2 -1 0 1 2at 1900.141 kb on + strand, within BT1540at 1900.216 kb on + strand, within BT1540at 1900.308 kb on + strandat 1900.343 kb on + strandat 1900.496 kb on + strand, within BT1541at 1900.513 kb on + strand, within BT1541at 1900.704 kb on + strand, within BT1541at 1900.723 kb on + strand, within BT1541at 1900.793 kb on - strand, within BT1541at 1900.827 kb on - strand, within BT1541at 1900.827 kb on - strand, within BT1541at 1901.062 kb on + strandat 1901.063 kb on - strandat 1901.063 kb on - strandat 1901.084 kb on - strandat 1901.125 kb on + strandat 1901.125 kb on + strandat 1901.125 kb on + strandat 1901.136 kb on + strandat 1901.139 kb on + strandat 1901.252 kb on + strandat 1901.260 kb on - strand, within BT1542at 1901.308 kb on + strand, within BT1542at 1901.326 kb on - strand, within BT1542at 1901.334 kb on + strand, within BT1542at 1901.335 kb on - strand, within BT1542at 1901.341 kb on + strand, within BT1542at 1901.342 kb on - strand, within BT1542at 1901.342 kb on - strand, within BT1542at 1901.434 kb on + strand, within BT1542at 1901.435 kb on - strand, within BT1542at 1901.443 kb on - strand, within BT1542at 1901.556 kb on + strand, within BT1542at 1901.556 kb on + strand, within BT1542at 1901.558 kb on + strand, within BT1542at 1901.558 kb on + strand, within BT1542at 1901.559 kb on - strand, within BT1542at 1901.588 kb on - strand, within BT1542at 1901.595 kb on + strand, within BT1542at 1901.638 kb on - strand, within BT1542at 1901.681 kb on - strand, within BT1542at 1901.884 kb on + strand, within BT1542at 1901.884 kb on + strand, within BT1542at 1902.009 kb on - strand, within BT1542at 1902.012 kb on + strand, within BT1542at 1902.027 kb on + strand, within BT1542at 1902.028 kb on - strand, within BT1542at 1902.028 kb on - strand, within BT1542at 1902.029 kb on + strand, within BT1542at 1902.030 kb on - strand, within BT1542at 1902.070 kb on + strand, within BT1542at 1902.164 kb on + strand, within BT1542at 1902.330 kb on + strand, within BT1542at 1902.330 kb on + strand, within BT1542at 1902.345 kb on + strand, within BT1542at 1902.345 kb on + strand, within BT1542at 1902.345 kb on + strand, within BT1542at 1902.346 kb on - strand, within BT1542at 1902.381 kb on + strandat 1902.382 kb on - strandat 1902.418 kb on - strandat 1902.418 kb on - strandat 1902.486 kb on - strandat 1902.611 kb on + strandat 1902.612 kb on - strandat 1902.617 kb on + strandat 1902.667 kb on - strandat 1902.688 kb on - strandat 1902.694 kb on - strandat 1902.694 kb on - strandat 1902.698 kb on - strandat 1902.698 kb on - strandat 1902.831 kb on - strandat 1902.845 kb on + strandat 1902.867 kb on + strandat 1902.867 kb on + strandat 1902.867 kb on + strandat 1902.868 kb on - strandat 1902.871 kb on + strandat 1902.872 kb on - strandat 1902.898 kb on - strandat 1902.912 kb on - strandat 1902.915 kb on - strandat 1902.984 kb on - strandat 1903.064 kb on - strandat 1903.064 kb on - strandat 1903.083 kb on - strandat 1903.104 kb on + strandat 1903.183 kb on + strandat 1903.256 kb on + strand, within BT1543at 1903.280 kb on + strand, within BT1543at 1903.314 kb on + strand, within BT1543at 1903.321 kb on + strand, within BT1543at 1903.343 kb on - strand, within BT1543at 1903.343 kb on - strand, within BT1543at 1903.460 kb on + strand, within BT1543

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Per-strain Table

Position Strand Gene LocusTag Fraction BHIS with Thioridazine 0.025 mM
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1,900,141 + BT1540 0.76 -2.1
1,900,216 + BT1540 0.85 -0.1
1,900,308 + +0.9
1,900,343 + -1.6
1,900,496 + BT1541 0.11 -0.1
1,900,513 + BT1541 0.14 -0.1
1,900,704 + BT1541 0.47 -3.3
1,900,723 + BT1541 0.50 -2.0
1,900,793 - BT1541 0.62 -0.6
1,900,827 - BT1541 0.68 +1.4
1,900,827 - BT1541 0.68 +2.2
1,901,062 + -2.1
1,901,063 - +1.7
1,901,063 - +2.0
1,901,084 - -0.1
1,901,125 + -2.1
1,901,125 + +0.2
1,901,125 + -3.7
1,901,136 + +0.4
1,901,139 + -3.8
1,901,252 + -1.1
1,901,260 - BT1542 0.10 -1.1
1,901,308 + BT1542 0.14 -3.5
1,901,326 - BT1542 0.15 -2.9
1,901,334 + BT1542 0.16 -3.6
1,901,335 - BT1542 0.16 -2.7
1,901,341 + BT1542 0.16 -0.1
1,901,342 - BT1542 0.16 +0.9
1,901,342 - BT1542 0.16 -3.6
1,901,434 + BT1542 0.23 -2.9
1,901,435 - BT1542 0.23 -0.1
1,901,443 - BT1542 0.24 +2.2
1,901,556 + BT1542 0.32 +2.2
1,901,556 + BT1542 0.32 -1.1
1,901,558 + BT1542 0.32 -3.0
1,901,558 + BT1542 0.32 -4.3
1,901,559 - BT1542 0.32 -3.8
1,901,588 - BT1542 0.34 -2.5
1,901,595 + BT1542 0.35 -1.1
1,901,638 - BT1542 0.38 -2.7
1,901,681 - BT1542 0.41 -0.9
1,901,884 + BT1542 0.56 -0.1
1,901,884 + BT1542 0.56 -2.4
1,902,009 - BT1542 0.65 -0.1
1,902,012 + BT1542 0.65 -0.9
1,902,027 + BT1542 0.66 -4.2
1,902,028 - BT1542 0.66 -0.7
1,902,028 - BT1542 0.66 -2.1
1,902,029 + BT1542 0.66 -2.5
1,902,030 - BT1542 0.67 -4.2
1,902,070 + BT1542 0.69 -4.1
1,902,164 + BT1542 0.76 -4.7
1,902,330 + BT1542 0.88 -1.7
1,902,330 + BT1542 0.88 -2.7
1,902,345 + BT1542 0.89 -2.5
1,902,345 + BT1542 0.89 +1.4
1,902,345 + BT1542 0.89 -1.7
1,902,346 - BT1542 0.90 -1.7
1,902,381 + -1.7
1,902,382 - -1.1
1,902,418 - -1.5
1,902,418 - -5.7
1,902,486 - -1.1
1,902,611 + +1.7
1,902,612 - -0.5
1,902,617 + -2.9
1,902,667 - +0.9
1,902,688 - -1.9
1,902,694 - -1.5
1,902,694 - -2.5
1,902,698 - -0.1
1,902,698 - -0.1
1,902,831 - -1.1
1,902,845 + +1.4
1,902,867 + -1.9
1,902,867 + -2.1
1,902,867 + -0.1
1,902,868 - +2.2
1,902,871 + -0.7
1,902,872 - -1.1
1,902,898 - -0.7
1,902,912 - -1.7
1,902,915 - -2.3
1,902,984 - -1.1
1,903,064 - -0.7
1,903,064 - -0.6
1,903,083 - -2.5
1,903,104 + -0.1
1,903,183 + -2.1
1,903,256 + BT1543 0.13 -2.5
1,903,280 + BT1543 0.14 -0.7
1,903,314 + BT1543 0.16 +1.2
1,903,321 + BT1543 0.17 -0.3
1,903,343 - BT1543 0.18 -2.9
1,903,343 - BT1543 0.18 -1.7
1,903,460 + BT1543 0.25 -0.1

Or see this region's nucleotide sequence