Experiment: McCas_formate_complete Rifampicin 0.25 mM
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt MMJJ_RS06925 and MMJJ_RS06930 are separated by 19 nucleotides MMJJ_RS06930 and MMJJ_RS06935 are separated by 10 nucleotides MMJJ_RS06935 and MMJJ_RS06940 are separated by 195 nucleotides MMJJ_RS06940 and MMJJ_RS06945 are separated by 110 nucleotides
MMJJ_RS06925: MMJJ_RS06925 - GMP synthase subunit A, at 1,271,154 to 1,271,723
_RS06925
MMJJ_RS06930: MMJJ_RS06930 - type II methionyl aminopeptidase, at 1,271,743 to 1,272,630
_RS06930
MMJJ_RS06935: MMJJ_RS06935 - GTP-binding protein, at 1,272,641 to 1,273,750
_RS06935
MMJJ_RS06940: MMJJ_RS06940 - metalloregulator ArsR/SmtB family transcription factor, at 1,273,946 to 1,274,233
_RS06940
MMJJ_RS06945: MMJJ_RS06945 - molybdopterin-guanine dinucleotide biosynthesis protein MobB, at 1,274,344 to 1,275,033
_RS06945
Position (kb) 1272
1273
1274 Strain fitness (log2 ratio) -5
-4
-3
-2
-1
0
1
2
3
4 at 1271.641 kb on + strand at 1271.688 kb on - strand at 1271.957 kb on + strand, within MMJJ_RS06930 at 1272.013 kb on + strand, within MMJJ_RS06930 at 1272.013 kb on + strand at 1272.160 kb on - strand, within MMJJ_RS06930 at 1272.161 kb on + strand, within MMJJ_RS06930 at 1272.277 kb on - strand, within MMJJ_RS06930 at 1272.328 kb on - strand, within MMJJ_RS06930 at 1272.554 kb on + strand at 1272.610 kb on + strand at 1272.671 kb on - strand at 1272.671 kb on - strand at 1272.672 kb on + strand at 1272.674 kb on + strand at 1272.674 kb on + strand at 1272.686 kb on - strand at 1272.740 kb on - strand at 1272.741 kb on + strand at 1272.741 kb on + strand at 1272.741 kb on + strand at 1272.787 kb on - strand, within MMJJ_RS06935 at 1272.787 kb on - strand, within MMJJ_RS06935 at 1272.788 kb on + strand, within MMJJ_RS06935 at 1272.820 kb on - strand, within MMJJ_RS06935 at 1272.820 kb on - strand, within MMJJ_RS06935 at 1272.825 kb on + strand, within MMJJ_RS06935 at 1272.863 kb on - strand, within MMJJ_RS06935 at 1272.863 kb on - strand, within MMJJ_RS06935 at 1272.867 kb on - strand, within MMJJ_RS06935 at 1272.947 kb on - strand, within MMJJ_RS06935 at 1273.024 kb on - strand, within MMJJ_RS06935 at 1273.025 kb on + strand, within MMJJ_RS06935 at 1273.041 kb on - strand, within MMJJ_RS06935 at 1273.055 kb on - strand, within MMJJ_RS06935 at 1273.055 kb on - strand, within MMJJ_RS06935 at 1273.101 kb on + strand, within MMJJ_RS06935 at 1273.106 kb on + strand, within MMJJ_RS06935 at 1273.145 kb on - strand, within MMJJ_RS06935 at 1273.161 kb on + strand, within MMJJ_RS06935 at 1273.250 kb on - strand, within MMJJ_RS06935 at 1273.256 kb on - strand, within MMJJ_RS06935 at 1273.256 kb on - strand, within MMJJ_RS06935 at 1273.281 kb on + strand, within MMJJ_RS06935 at 1273.282 kb on - strand, within MMJJ_RS06935 at 1273.283 kb on + strand, within MMJJ_RS06935 at 1273.304 kb on - strand, within MMJJ_RS06935 at 1273.304 kb on - strand, within MMJJ_RS06935 at 1273.322 kb on - strand, within MMJJ_RS06935 at 1273.322 kb on - strand, within MMJJ_RS06935 at 1273.323 kb on + strand, within MMJJ_RS06935 at 1273.396 kb on - strand, within MMJJ_RS06935 at 1273.433 kb on + strand, within MMJJ_RS06935 at 1273.433 kb on + strand, within MMJJ_RS06935 at 1273.433 kb on + strand, within MMJJ_RS06935 at 1273.453 kb on - strand, within MMJJ_RS06935 at 1273.459 kb on - strand, within MMJJ_RS06935 at 1273.504 kb on - strand, within MMJJ_RS06935 at 1273.504 kb on - strand, within MMJJ_RS06935 at 1273.580 kb on + strand, within MMJJ_RS06935 at 1273.661 kb on - strand at 1273.662 kb on + strand at 1273.666 kb on - strand at 1273.667 kb on + strand at 1273.690 kb on - strand at 1273.693 kb on - strand at 1273.702 kb on - strand at 1273.706 kb on - strand at 1273.706 kb on - strand at 1273.707 kb on + strand at 1273.709 kb on - strand at 1273.709 kb on - strand at 1273.710 kb on + strand at 1273.710 kb on + strand at 1273.865 kb on + strand at 1273.878 kb on - strand at 1273.879 kb on + strand at 1273.884 kb on - strand at 1273.886 kb on - strand at 1273.887 kb on + strand at 1273.887 kb on + strand at 1273.887 kb on + strand at 1273.887 kb on + strand at 1273.887 kb on + strand at 1273.894 kb on + strand at 1273.902 kb on + strand at 1273.905 kb on - strand at 1273.906 kb on + strand at 1273.906 kb on + strand at 1273.906 kb on + strand at 1273.908 kb on + strand at 1273.927 kb on + strand at 1273.935 kb on - strand at 1273.938 kb on - strand at 1273.938 kb on - strand at 1273.939 kb on + strand at 1273.941 kb on + strand at 1273.948 kb on + strand at 1273.953 kb on + strand at 1273.966 kb on - strand at 1273.969 kb on - strand at 1273.969 kb on - strand at 1273.969 kb on - strand at 1273.970 kb on + strand at 1273.970 kb on + strand at 1273.970 kb on + strand at 1273.970 kb on + strand at 1273.970 kb on + strand at 1273.973 kb on - strand at 1273.973 kb on - strand at 1273.974 kb on + strand at 1273.974 kb on + strand at 1273.974 kb on + strand at 1273.997 kb on - strand, within MMJJ_RS06940 at 1273.998 kb on + strand, within MMJJ_RS06940 at 1274.003 kb on + strand, within MMJJ_RS06940 at 1274.004 kb on - strand, within MMJJ_RS06940 at 1274.004 kb on - strand, within MMJJ_RS06940 at 1274.004 kb on - strand, within MMJJ_RS06940 at 1274.004 kb on - strand, within MMJJ_RS06940 at 1274.004 kb on - strand, within MMJJ_RS06940 at 1274.005 kb on + strand, within MMJJ_RS06940 at 1274.005 kb on + strand, within MMJJ_RS06940 at 1274.005 kb on + strand, within MMJJ_RS06940 at 1274.005 kb on + strand, within MMJJ_RS06940 at 1274.005 kb on + strand, within MMJJ_RS06940 at 1274.005 kb on + strand, within MMJJ_RS06940 at 1274.005 kb on + strand, within MMJJ_RS06940 at 1274.032 kb on - strand, within MMJJ_RS06940 at 1274.039 kb on + strand, within MMJJ_RS06940 at 1274.060 kb on - strand, within MMJJ_RS06940 at 1274.060 kb on - strand, within MMJJ_RS06940 at 1274.060 kb on - strand, within MMJJ_RS06940 at 1274.060 kb on - strand, within MMJJ_RS06940 at 1274.060 kb on - strand, within MMJJ_RS06940 at 1274.061 kb on + strand, within MMJJ_RS06940 at 1274.066 kb on - strand, within MMJJ_RS06940 at 1274.066 kb on - strand, within MMJJ_RS06940 at 1274.066 kb on - strand, within MMJJ_RS06940 at 1274.067 kb on + strand, within MMJJ_RS06940 at 1274.067 kb on + strand, within MMJJ_RS06940 at 1274.111 kb on + strand, within MMJJ_RS06940 at 1274.116 kb on - strand, within MMJJ_RS06940 at 1274.129 kb on + strand, within MMJJ_RS06940 at 1274.129 kb on + strand, within MMJJ_RS06940 at 1274.129 kb on + strand, within MMJJ_RS06940 at 1274.144 kb on - strand, within MMJJ_RS06940 at 1274.167 kb on - strand, within MMJJ_RS06940 at 1274.167 kb on - strand, within MMJJ_RS06940 at 1274.168 kb on + strand, within MMJJ_RS06940 at 1274.203 kb on - strand, within MMJJ_RS06940 at 1274.203 kb on - strand, within MMJJ_RS06940 at 1274.203 kb on - strand, within MMJJ_RS06940 at 1274.204 kb on + strand, within MMJJ_RS06940 at 1274.205 kb on - strand at 1274.206 kb on + strand at 1274.206 kb on + strand at 1274.206 kb on + strand at 1274.206 kb on + strand at 1274.206 kb on + strand at 1274.206 kb on + strand at 1274.211 kb on - strand at 1274.211 kb on - strand at 1274.211 kb on - strand at 1274.211 kb on - strand at 1274.217 kb on - strand at 1274.218 kb on + strand at 1274.225 kb on - strand at 1274.226 kb on + strand at 1274.226 kb on + strand at 1274.226 kb on + strand at 1274.226 kb on + strand at 1274.227 kb on - strand at 1274.252 kb on - strand at 1274.253 kb on + strand at 1274.255 kb on - strand at 1274.255 kb on - strand at 1274.255 kb on - strand at 1274.256 kb on + strand at 1274.256 kb on + strand at 1274.256 kb on + strand at 1274.257 kb on - strand at 1274.257 kb on - strand at 1274.257 kb on - strand at 1274.258 kb on + strand at 1274.258 kb on + strand at 1274.258 kb on + strand at 1274.317 kb on - strand at 1274.328 kb on + strand at 1274.404 kb on - strand at 1274.404 kb on - strand at 1274.404 kb on - strand at 1274.404 kb on - strand at 1274.404 kb on - strand at 1274.405 kb on + strand at 1274.405 kb on + strand at 1274.416 kb on - strand, within MMJJ_RS06945 at 1274.416 kb on - strand, within MMJJ_RS06945 at 1274.416 kb on - strand, within MMJJ_RS06945 at 1274.417 kb on + strand, within MMJJ_RS06945 at 1274.417 kb on + strand, within MMJJ_RS06945 at 1274.417 kb on + strand, within MMJJ_RS06945 at 1274.418 kb on - strand, within MMJJ_RS06945 at 1274.418 kb on - strand, within MMJJ_RS06945 at 1274.429 kb on + strand, within MMJJ_RS06945 at 1274.429 kb on + strand, within MMJJ_RS06945 at 1274.430 kb on - strand at 1274.477 kb on + strand, within MMJJ_RS06945 at 1274.499 kb on - strand, within MMJJ_RS06945 at 1274.499 kb on - strand, within MMJJ_RS06945 at 1274.500 kb on + strand, within MMJJ_RS06945 at 1274.500 kb on + strand, within MMJJ_RS06945 at 1274.517 kb on - strand, within MMJJ_RS06945 at 1274.517 kb on - strand, within MMJJ_RS06945 at 1274.561 kb on - strand, within MMJJ_RS06945 at 1274.589 kb on + strand, within MMJJ_RS06945 at 1274.600 kb on + strand, within MMJJ_RS06945 at 1274.601 kb on - strand, within MMJJ_RS06945 at 1274.635 kb on - strand, within MMJJ_RS06945 at 1274.635 kb on - strand, within MMJJ_RS06945 at 1274.684 kb on + strand, within MMJJ_RS06945 at 1274.711 kb on + strand, within MMJJ_RS06945 at 1274.711 kb on + strand, within MMJJ_RS06945 at 1274.727 kb on - strand, within MMJJ_RS06945 at 1274.731 kb on - strand, within MMJJ_RS06945
Per-strain Table
Position Strand Gene LocusTag Fraction McCas_formate_complete Rifampicin 0.25 mM remove 1,271,641 + +1.2 1,271,688 - -0.4 1,271,957 + MMJJ_RS06930 0.24 +1.2 1,272,013 + MMJJ_RS06930 0.30 -1.7 1,272,013 + -0.2 1,272,160 - MMJJ_RS06930 0.47 -2.3 1,272,161 + MMJJ_RS06930 0.47 -1.4 1,272,277 - MMJJ_RS06930 0.60 -0.8 1,272,328 - MMJJ_RS06930 0.66 -1.9 1,272,554 + -0.4 1,272,610 + -0.8 1,272,671 - -3.9 1,272,671 - -1.8 1,272,672 + -0.4 1,272,674 + -2.2 1,272,674 + -2.5 1,272,686 - -0.3 1,272,740 - -1.5 1,272,741 + -1.7 1,272,741 + -1.4 1,272,741 + -1.1 1,272,787 - MMJJ_RS06935 0.13 -3.8 1,272,787 - MMJJ_RS06935 0.13 +0.4 1,272,788 + MMJJ_RS06935 0.13 -1.3 1,272,820 - MMJJ_RS06935 0.16 -3.3 1,272,820 - MMJJ_RS06935 0.16 -2.3 1,272,825 + MMJJ_RS06935 0.17 -0.4 1,272,863 - MMJJ_RS06935 0.20 -2.3 1,272,863 - MMJJ_RS06935 0.20 -1.5 1,272,867 - MMJJ_RS06935 0.20 +0.1 1,272,947 - MMJJ_RS06935 0.28 -3.9 1,273,024 - MMJJ_RS06935 0.35 -2.4 1,273,025 + MMJJ_RS06935 0.35 -0.7 1,273,041 - MMJJ_RS06935 0.36 -1.5 1,273,055 - MMJJ_RS06935 0.37 -2.4 1,273,055 - MMJJ_RS06935 0.37 -1.9 1,273,101 + MMJJ_RS06935 0.41 -2.0 1,273,106 + MMJJ_RS06935 0.42 -1.4 1,273,145 - MMJJ_RS06935 0.45 +0.9 1,273,161 + MMJJ_RS06935 0.47 -2.1 1,273,250 - MMJJ_RS06935 0.55 -4.2 1,273,256 - MMJJ_RS06935 0.55 -0.4 1,273,256 - MMJJ_RS06935 0.55 -4.0 1,273,281 + MMJJ_RS06935 0.58 -1.5 1,273,282 - MMJJ_RS06935 0.58 -3.3 1,273,283 + MMJJ_RS06935 0.58 -3.9 1,273,304 - MMJJ_RS06935 0.60 -3.4 1,273,304 - MMJJ_RS06935 0.60 -0.6 1,273,322 - MMJJ_RS06935 0.61 -2.5 1,273,322 - MMJJ_RS06935 0.61 -1.9 1,273,323 + MMJJ_RS06935 0.61 -3.5 1,273,396 - MMJJ_RS06935 0.68 -0.9 1,273,433 + MMJJ_RS06935 0.71 -0.2 1,273,433 + MMJJ_RS06935 0.71 -2.8 1,273,433 + MMJJ_RS06935 0.71 -1.8 1,273,453 - MMJJ_RS06935 0.73 -2.1 1,273,459 - MMJJ_RS06935 0.74 -1.6 1,273,504 - MMJJ_RS06935 0.78 -3.4 1,273,504 - MMJJ_RS06935 0.78 -3.8 1,273,580 + MMJJ_RS06935 0.85 -3.8 1,273,661 - -3.8 1,273,662 + -1.8 1,273,666 - -3.2 1,273,667 + +0.2 1,273,690 - -1.7 1,273,693 - -4.6 1,273,702 - -2.2 1,273,706 - -0.1 1,273,706 - -1.6 1,273,707 + -2.5 1,273,709 - -4.5 1,273,709 - -3.2 1,273,710 + +1.4 1,273,710 + -1.7 1,273,865 + -0.7 1,273,878 - -1.7 1,273,879 + +0.2 1,273,884 - -1.4 1,273,886 - -2.1 1,273,887 + -0.0 1,273,887 + -0.4 1,273,887 + -1.5 1,273,887 + -1.0 1,273,887 + -0.6 1,273,894 + -0.1 1,273,902 + -2.4 1,273,905 - +1.4 1,273,906 + -0.2 1,273,906 + -0.8 1,273,906 + -2.3 1,273,908 + +0.8 1,273,927 + +0.0 1,273,935 - +1.8 1,273,938 - +0.3 1,273,938 - -3.8 1,273,939 + -0.1 1,273,941 + +0.4 1,273,948 + -0.3 1,273,953 + +2.8 1,273,966 - +0.1 1,273,969 - -2.6 1,273,969 - +0.4 1,273,969 - +2.8 1,273,970 + +1.5 1,273,970 + +1.9 1,273,970 + +1.9 1,273,970 + +1.3 1,273,970 + -0.4 1,273,973 - -0.5 1,273,973 - +1.8 1,273,974 + +0.5 1,273,974 + -4.1 1,273,974 + +0.3 1,273,997 - MMJJ_RS06940 0.18 -1.3 1,273,998 + MMJJ_RS06940 0.18 +1.0 1,274,003 + MMJJ_RS06940 0.20 -1.8 1,274,004 - MMJJ_RS06940 0.20 -1.7 1,274,004 - MMJJ_RS06940 0.20 -3.5 1,274,004 - MMJJ_RS06940 0.20 -3.2 1,274,004 - MMJJ_RS06940 0.20 -3.1 1,274,004 - MMJJ_RS06940 0.20 +1.2 1,274,005 + MMJJ_RS06940 0.20 -2.7 1,274,005 + MMJJ_RS06940 0.20 -1.2 1,274,005 + MMJJ_RS06940 0.20 -2.3 1,274,005 + MMJJ_RS06940 0.20 -3.3 1,274,005 + MMJJ_RS06940 0.20 -0.1 1,274,005 + MMJJ_RS06940 0.20 -2.5 1,274,005 + MMJJ_RS06940 0.20 -0.8 1,274,032 - MMJJ_RS06940 0.30 -1.8 1,274,039 + MMJJ_RS06940 0.32 -1.7 1,274,060 - MMJJ_RS06940 0.40 -1.5 1,274,060 - MMJJ_RS06940 0.40 -0.1 1,274,060 - MMJJ_RS06940 0.40 -2.6 1,274,060 - MMJJ_RS06940 0.40 -3.1 1,274,060 - MMJJ_RS06940 0.40 -3.1 1,274,061 + MMJJ_RS06940 0.40 -1.0 1,274,066 - MMJJ_RS06940 0.42 -3.5 1,274,066 - MMJJ_RS06940 0.42 -1.0 1,274,066 - MMJJ_RS06940 0.42 -3.7 1,274,067 + MMJJ_RS06940 0.42 -2.2 1,274,067 + MMJJ_RS06940 0.42 -3.3 1,274,111 + MMJJ_RS06940 0.57 +0.6 1,274,116 - MMJJ_RS06940 0.59 -0.4 1,274,129 + MMJJ_RS06940 0.64 -2.7 1,274,129 + MMJJ_RS06940 0.64 -0.4 1,274,129 + MMJJ_RS06940 0.64 -2.6 1,274,144 - MMJJ_RS06940 0.69 -4.4 1,274,167 - MMJJ_RS06940 0.77 -1.0 1,274,167 - MMJJ_RS06940 0.77 -1.1 1,274,168 + MMJJ_RS06940 0.77 +2.2 1,274,203 - MMJJ_RS06940 0.89 -2.6 1,274,203 - MMJJ_RS06940 0.89 -0.6 1,274,203 - MMJJ_RS06940 0.89 -0.1 1,274,204 + MMJJ_RS06940 0.90 -2.1 1,274,205 - -3.1 1,274,206 + -2.3 1,274,206 + -0.7 1,274,206 + -2.5 1,274,206 + -3.0 1,274,206 + -2.1 1,274,206 + -2.9 1,274,211 - -1.0 1,274,211 - +0.6 1,274,211 - +0.6 1,274,211 - -3.1 1,274,217 - -2.1 1,274,218 + -1.3 1,274,225 - -0.0 1,274,226 + -5.3 1,274,226 + +0.2 1,274,226 + -2.4 1,274,226 + -3.0 1,274,227 - -2.2 1,274,252 - -3.0 1,274,253 + -2.1 1,274,255 - -2.5 1,274,255 - -0.1 1,274,255 - +0.2 1,274,256 + -2.0 1,274,256 + +0.6 1,274,256 + +0.0 1,274,257 - +0.2 1,274,257 - -1.1 1,274,257 - -1.1 1,274,258 + -4.5 1,274,258 + -2.8 1,274,258 + -3.0 1,274,317 - +3.6 1,274,328 + +1.6 1,274,404 - +1.3 1,274,404 - +2.4 1,274,404 - +2.7 1,274,404 - +1.8 1,274,404 - +3.1 1,274,405 + +2.1 1,274,405 + -2.3 1,274,416 - MMJJ_RS06945 0.10 +2.3 1,274,416 - MMJJ_RS06945 0.10 +1.6 1,274,416 - MMJJ_RS06945 0.10 +2.0 1,274,417 + MMJJ_RS06945 0.11 +1.4 1,274,417 + MMJJ_RS06945 0.11 +3.6 1,274,417 + MMJJ_RS06945 0.11 +3.4 1,274,418 - MMJJ_RS06945 0.11 +0.7 1,274,418 - MMJJ_RS06945 0.11 +2.7 1,274,429 + MMJJ_RS06945 0.12 +4.0 1,274,429 + MMJJ_RS06945 0.12 +2.9 1,274,430 - -0.1 1,274,477 + MMJJ_RS06945 0.19 +1.4 1,274,499 - MMJJ_RS06945 0.22 +1.1 1,274,499 - MMJJ_RS06945 0.22 +1.7 1,274,500 + MMJJ_RS06945 0.23 +1.1 1,274,500 + MMJJ_RS06945 0.23 +1.9 1,274,517 - MMJJ_RS06945 0.25 +3.3 1,274,517 - MMJJ_RS06945 0.25 -0.0 1,274,561 - MMJJ_RS06945 0.31 +1.2 1,274,589 + MMJJ_RS06945 0.36 +1.8 1,274,600 + MMJJ_RS06945 0.37 +3.6 1,274,601 - MMJJ_RS06945 0.37 +1.9 1,274,635 - MMJJ_RS06945 0.42 +1.7 1,274,635 - MMJJ_RS06945 0.42 +1.6 1,274,684 + MMJJ_RS06945 0.49 +1.9 1,274,711 + MMJJ_RS06945 0.53 +1.8 1,274,711 + MMJJ_RS06945 0.53 +2.0 1,274,727 - MMJJ_RS06945 0.56 +2.9 1,274,731 - MMJJ_RS06945 0.56 +1.6
Or see this region's nucleotide sequence