Experiment: m.b. Ceftazidime 0.032 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt HP15_15 and HP15_16 are separated by 7 nucleotides HP15_16 and HP15_17 are separated by 663 nucleotides HP15_17 and HP15_18 overlap by 17 nucleotides
HP15_15: HP15_15 - short chain dehydrogenase/reductase, at 17,567 to 18,214
_15
HP15_16: HP15_16 - glyoxalase/bleomycin resistance protein/dioxygenase-like protein, at 18,222 to 18,392
_16
HP15_17: HP15_17 - FAD-dependent oxidoreductase, at 19,056 to 20,900
_17
HP15_18: HP15_18 - cytochrome P450 monooxygenase, at 20,884 to 22,161
_18
Position (kb) 19
20
21 Strain fitness (log2 ratio) -2
-1
0
1 at 18.107 kb on + strand, within HP15_15 at 18.115 kb on - strand, within HP15_15 at 18.155 kb on + strand at 18.211 kb on - strand at 18.217 kb on + strand at 18.374 kb on + strand, within HP15_16 at 18.374 kb on + strand, within HP15_16 at 18.374 kb on + strand, within HP15_16 at 18.379 kb on + strand at 18.382 kb on - strand at 18.382 kb on - strand at 18.382 kb on - strand at 18.384 kb on + strand at 18.392 kb on - strand at 18.392 kb on - strand at 18.392 kb on - strand at 18.426 kb on + strand at 18.434 kb on - strand at 18.434 kb on - strand at 18.445 kb on + strand at 18.459 kb on + strand at 18.466 kb on - strand at 18.466 kb on - strand at 18.466 kb on - strand at 18.556 kb on - strand at 18.577 kb on - strand at 18.596 kb on + strand at 18.615 kb on - strand at 18.673 kb on + strand at 18.694 kb on - strand at 18.761 kb on - strand at 18.773 kb on + strand at 18.774 kb on + strand at 18.785 kb on + strand at 18.787 kb on + strand at 18.798 kb on - strand at 18.938 kb on + strand at 19.063 kb on + strand at 19.141 kb on + strand at 19.150 kb on + strand at 19.259 kb on + strand, within HP15_17 at 19.260 kb on + strand, within HP15_17 at 19.301 kb on - strand, within HP15_17 at 19.306 kb on - strand, within HP15_17 at 19.329 kb on - strand, within HP15_17 at 19.424 kb on - strand, within HP15_17 at 19.510 kb on - strand, within HP15_17 at 19.517 kb on + strand, within HP15_17 at 19.523 kb on - strand, within HP15_17 at 19.533 kb on - strand, within HP15_17 at 19.628 kb on + strand, within HP15_17 at 19.654 kb on + strand, within HP15_17 at 19.654 kb on + strand, within HP15_17 at 19.746 kb on + strand, within HP15_17 at 19.766 kb on + strand, within HP15_17 at 19.856 kb on - strand, within HP15_17 at 19.935 kb on - strand, within HP15_17 at 20.005 kb on + strand, within HP15_17 at 20.005 kb on - strand, within HP15_17 at 20.014 kb on - strand, within HP15_17 at 20.064 kb on + strand, within HP15_17 at 20.084 kb on + strand, within HP15_17 at 20.084 kb on + strand, within HP15_17 at 20.104 kb on + strand, within HP15_17 at 20.133 kb on + strand, within HP15_17 at 20.152 kb on + strand, within HP15_17 at 20.167 kb on - strand, within HP15_17 at 20.230 kb on + strand, within HP15_17 at 20.238 kb on - strand, within HP15_17 at 20.271 kb on - strand, within HP15_17 at 20.285 kb on - strand, within HP15_17 at 20.313 kb on + strand, within HP15_17 at 20.358 kb on - strand, within HP15_17 at 20.379 kb on + strand, within HP15_17 at 20.395 kb on + strand, within HP15_17 at 20.403 kb on - strand, within HP15_17 at 20.463 kb on + strand, within HP15_17 at 20.513 kb on + strand, within HP15_17 at 20.516 kb on - strand, within HP15_17 at 20.520 kb on - strand, within HP15_17 at 20.617 kb on + strand, within HP15_17 at 20.634 kb on + strand, within HP15_17 at 20.634 kb on + strand, within HP15_17 at 20.635 kb on - strand, within HP15_17 at 20.665 kb on + strand, within HP15_17 at 20.701 kb on - strand, within HP15_17 at 20.708 kb on - strand, within HP15_17 at 20.737 kb on + strand at 20.808 kb on - strand at 20.925 kb on - strand at 20.966 kb on + strand at 20.967 kb on - strand at 20.974 kb on - strand at 20.974 kb on - strand at 20.974 kb on - strand at 20.974 kb on - strand at 20.994 kb on + strand at 21.002 kb on - strand at 21.032 kb on + strand, within HP15_18 at 21.032 kb on + strand, within HP15_18 at 21.057 kb on + strand, within HP15_18 at 21.077 kb on + strand, within HP15_18 at 21.102 kb on - strand, within HP15_18 at 21.164 kb on - strand, within HP15_18 at 21.179 kb on + strand, within HP15_18 at 21.213 kb on - strand, within HP15_18 at 21.213 kb on - strand, within HP15_18 at 21.213 kb on - strand, within HP15_18 at 21.266 kb on + strand, within HP15_18 at 21.303 kb on + strand, within HP15_18 at 21.345 kb on - strand, within HP15_18 at 21.378 kb on - strand, within HP15_18 at 21.439 kb on + strand, within HP15_18 at 21.447 kb on - strand, within HP15_18 at 21.447 kb on - strand, within HP15_18 at 21.447 kb on - strand, within HP15_18 at 21.447 kb on - strand, within HP15_18 at 21.458 kb on - strand, within HP15_18 at 21.550 kb on + strand, within HP15_18 at 21.558 kb on - strand, within HP15_18 at 21.600 kb on + strand, within HP15_18 at 21.628 kb on + strand, within HP15_18 at 21.643 kb on - strand, within HP15_18 at 21.644 kb on - strand, within HP15_18 at 21.708 kb on + strand, within HP15_18 at 21.715 kb on + strand, within HP15_18 at 21.809 kb on - strand, within HP15_18
Per-strain Table
Position Strand Gene LocusTag Fraction m.b. Ceftazidime 0.032 mg/ml remove 18,107 + HP15_15 0.83 -0.5 18,115 - HP15_15 0.85 +0.6 18,155 + -0.2 18,211 - -0.1 18,217 + +0.0 18,374 + HP15_16 0.89 +0.6 18,374 + HP15_16 0.89 -0.2 18,374 + HP15_16 0.89 -0.1 18,379 + +0.1 18,382 - -0.4 18,382 - +0.2 18,382 - -0.5 18,384 + -0.4 18,392 - -0.1 18,392 - -1.9 18,392 - -0.2 18,426 + +0.0 18,434 - -0.1 18,434 - -0.4 18,445 + +0.3 18,459 + -0.1 18,466 - +0.0 18,466 - +0.1 18,466 - +0.6 18,556 - -0.5 18,577 - -1.7 18,596 + -0.2 18,615 - -0.3 18,673 + +0.1 18,694 - -0.4 18,761 - +0.3 18,773 + -0.2 18,774 + +0.1 18,785 + -1.5 18,787 + -0.2 18,798 - +0.5 18,938 + -0.1 19,063 + -1.2 19,141 + -0.1 19,150 + -0.3 19,259 + HP15_17 0.11 +0.1 19,260 + HP15_17 0.11 +0.4 19,301 - HP15_17 0.13 +0.3 19,306 - HP15_17 0.14 -0.3 19,329 - HP15_17 0.15 +0.6 19,424 - HP15_17 0.20 -0.6 19,510 - HP15_17 0.25 +0.0 19,517 + HP15_17 0.25 -0.2 19,523 - HP15_17 0.25 -0.3 19,533 - HP15_17 0.26 -0.2 19,628 + HP15_17 0.31 +0.3 19,654 + HP15_17 0.32 -0.2 19,654 + HP15_17 0.32 -0.1 19,746 + HP15_17 0.37 -0.2 19,766 + HP15_17 0.38 -0.6 19,856 - HP15_17 0.43 -0.5 19,935 - HP15_17 0.48 -0.6 20,005 + HP15_17 0.51 -0.2 20,005 - HP15_17 0.51 -0.2 20,014 - HP15_17 0.52 -0.2 20,064 + HP15_17 0.55 -0.0 20,084 + HP15_17 0.56 -0.2 20,084 + HP15_17 0.56 -0.5 20,104 + HP15_17 0.57 -0.2 20,133 + HP15_17 0.58 -0.3 20,152 + HP15_17 0.59 +0.0 20,167 - HP15_17 0.60 +0.0 20,230 + HP15_17 0.64 -0.1 20,238 - HP15_17 0.64 -0.2 20,271 - HP15_17 0.66 +0.1 20,285 - HP15_17 0.67 -0.3 20,313 + HP15_17 0.68 -0.1 20,358 - HP15_17 0.71 +0.5 20,379 + HP15_17 0.72 -0.3 20,395 + HP15_17 0.73 +0.1 20,403 - HP15_17 0.73 -0.1 20,463 + HP15_17 0.76 -0.5 20,513 + HP15_17 0.79 -0.1 20,516 - HP15_17 0.79 -0.4 20,520 - HP15_17 0.79 -0.6 20,617 + HP15_17 0.85 +0.9 20,634 + HP15_17 0.86 -0.2 20,634 + HP15_17 0.86 +0.7 20,635 - HP15_17 0.86 -0.5 20,665 + HP15_17 0.87 -0.3 20,701 - HP15_17 0.89 -1.0 20,708 - HP15_17 0.90 -0.0 20,737 + -0.3 20,808 - +0.6 20,925 - -0.1 20,966 + -0.2 20,967 - -0.4 20,974 - -0.5 20,974 - -0.4 20,974 - +0.0 20,974 - -0.1 20,994 + -0.5 21,002 - +0.4 21,032 + HP15_18 0.12 -0.2 21,032 + HP15_18 0.12 +0.2 21,057 + HP15_18 0.14 -0.4 21,077 + HP15_18 0.15 -0.3 21,102 - HP15_18 0.17 +0.2 21,164 - HP15_18 0.22 +0.3 21,179 + HP15_18 0.23 +0.7 21,213 - HP15_18 0.26 +0.1 21,213 - HP15_18 0.26 -0.3 21,213 - HP15_18 0.26 -0.2 21,266 + HP15_18 0.30 +0.6 21,303 + HP15_18 0.33 +0.0 21,345 - HP15_18 0.36 -0.5 21,378 - HP15_18 0.39 -0.5 21,439 + HP15_18 0.43 +0.1 21,447 - HP15_18 0.44 +0.1 21,447 - HP15_18 0.44 +0.4 21,447 - HP15_18 0.44 -0.6 21,447 - HP15_18 0.44 -0.5 21,458 - HP15_18 0.45 +0.5 21,550 + HP15_18 0.52 +0.0 21,558 - HP15_18 0.53 -0.3 21,600 + HP15_18 0.56 -0.3 21,628 + HP15_18 0.58 -0.3 21,643 - HP15_18 0.59 -0.1 21,644 - HP15_18 0.59 +0.8 21,708 + HP15_18 0.64 +0.3 21,715 + HP15_18 0.65 +0.0 21,809 - HP15_18 0.72 -0.6
Or see this region's nucleotide sequence