Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3453

Experiment: 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Hydrogen peroxide 2.5 mM; pH 6.5
3,873,418	-				-1.8
3,873,418	-				-0.2
3,873,426	-				-0.3
3,873,556	+		Rv3452	0.15	-0.5
3,873,557	+		Rv3452	0.15	-0.3
3,873,708	-		Rv3452	0.38	+0.7
3,873,708	-		Rv3452	0.38	-0.7
3,873,708	-		Rv3452	0.38	-1.8
3,873,708	-		Rv3452	0.38	-1.0
3,874,074	+				-0.8
3,874,074	+				-0.6
3,874,074	+				-0.1
3,874,080	-				-0.5
3,874,080	-				-1.0
3,874,130	+				-0.8
3,874,147	+				-1.7
3,874,148	-				-0.5
3,874,148	-				+0.2
3,874,217	+				-1.6
3,874,229	-				-1.6
3,874,417	+				-0.4
3,874,489	-		Rv3453	0.26	+0.0
3,874,605	-		Rv3453	0.60	-1.2
3,874,687	-		Rv3453	0.85	-0.6
3,874,689	+		Rv3453	0.86	-0.4
3,874,690	-		Rv3453	0.86	-1.7
3,874,702	-		Rv3453	0.89	-0.5
3,874,747	+				-0.7
3,874,841	+				+0.1
3,874,841	+				+0.7
3,874,842	-				-0.4
3,874,842	-				+0.6
3,874,988	-		Rv3454	0.13	-0.3
3,875,264	-		Rv3454	0.35	-1.1
3,875,264	-		Rv3454	0.35	-0.4
3,875,264	-		Rv3454	0.35	+0.7
3,875,682	-		Rv3454	0.68	+0.1
3,875,684	-		Rv3454	0.68	-0.3