Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3424c

Experiment: 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3423c and Rv3424c are separated by 293 nucleotidesRv3424c and Rv3425 are separated by 162 nucleotidesRv3425 and Rv3426 are separated by 266 nucleotides Rv3423c: Rv3423c - Alanine racemase Alr, at 3,840,194 to 3,841,420 Rv3423c Rv3424c: Rv3424c - Hypothetical protein, at 3,841,714 to 3,842,076 Rv3424c Rv3425: Rv3425 - PPE family protein PPE57, at 3,842,239 to 3,842,769 Rv3425 Rv3426: Rv3426 - PPE family protein PPE58, at 3,843,036 to 3,843,734 Rv3426 Position (kb) 3841 3842 3843Strain fitness (log2 ratio) -2 -1 0 1at 3841.429 kb on - strandat 3841.572 kb on - strandat 3841.835 kb on + strand, within Rv3424cat 3841.836 kb on - strand, within Rv3424cat 3842.409 kb on + strand, within Rv3425at 3842.409 kb on + strand, within Rv3425at 3842.410 kb on - strand, within Rv3425at 3842.447 kb on - strand, within Rv3425at 3842.464 kb on - strand, within Rv3425at 3842.482 kb on - strand, within Rv3425at 3842.521 kb on + strand, within Rv3425at 3842.546 kb on + strand, within Rv3425at 3842.546 kb on + strand, within Rv3425at 3842.615 kb on + strand, within Rv3425at 3842.616 kb on - strand, within Rv3425at 3842.650 kb on + strand, within Rv3425at 3842.660 kb on - strand, within Rv3425at 3842.681 kb on + strand, within Rv3425at 3842.696 kb on + strand, within Rv3425at 3842.696 kb on + strand, within Rv3425at 3842.696 kb on + strand, within Rv3425at 3842.696 kb on + strand, within Rv3425at 3842.696 kb on + strand, within Rv3425at 3842.696 kb on + strand, within Rv3425at 3842.697 kb on - strand, within Rv3425at 3842.697 kb on - strand, within Rv3425at 3842.697 kb on - strand, within Rv3425at 3842.697 kb on - strand, within Rv3425at 3842.697 kb on - strand, within Rv3425at 3842.756 kb on - strandat 3842.894 kb on + strandat 3842.894 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5
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3,841,429 - -0.8
3,841,572 - -2.4
3,841,835 + Rv3424c 0.33 +0.4
3,841,836 - Rv3424c 0.34 -0.2
3,842,409 + Rv3425 0.32 +0.7
3,842,409 + Rv3425 0.32 -0.2
3,842,410 - Rv3425 0.32 -0.7
3,842,447 - Rv3425 0.39 -0.6
3,842,464 - Rv3425 0.42 -0.1
3,842,482 - Rv3425 0.46 +0.2
3,842,521 + Rv3425 0.53 +1.1
3,842,546 + Rv3425 0.58 -0.8
3,842,546 + Rv3425 0.58 -2.1
3,842,615 + Rv3425 0.71 -1.1
3,842,616 - Rv3425 0.71 +0.4
3,842,650 + Rv3425 0.77 -0.7
3,842,660 - Rv3425 0.79 +0.9
3,842,681 + Rv3425 0.83 +0.1
3,842,696 + Rv3425 0.86 -0.6
3,842,696 + Rv3425 0.86 -0.1
3,842,696 + Rv3425 0.86 -0.2
3,842,696 + Rv3425 0.86 +0.1
3,842,696 + Rv3425 0.86 -0.6
3,842,696 + Rv3425 0.86 -1.7
3,842,697 - Rv3425 0.86 -1.1
3,842,697 - Rv3425 0.86 -0.9
3,842,697 - Rv3425 0.86 -0.1
3,842,697 - Rv3425 0.86 -0.3
3,842,697 - Rv3425 0.86 -1.2
3,842,756 - -0.9
3,842,894 + -0.1
3,842,894 + -1.6

Or see this region's nucleotide sequence