Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3261

Experiment: 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3259 and Rv3260c are separated by 27 nucleotidesRv3260c and Rv3261 are separated by 401 nucleotidesRv3261 and Rv3262 overlap by 4 nucleotides Rv3259: Rv3259 - Conserved hypothetical protein, at 3,639,425 to 3,639,844 Rv3259 Rv3260c: Rv3260c - Probable transcriptional regulatory protein WhiB-like WhiB2, at 3,639,872 to 3,640,141 Rv3260c Rv3261: Rv3261 - Probable F420 biosynthesis protein FbiA, at 3,640,543 to 3,641,538 Rv3261 Rv3262: Rv3262 - Probable F420 biosynthesis protein FbiB, at 3,641,535 to 3,642,881 Rv3262 Position (kb) 3640 3641 3642Strain fitness (log2 ratio) -2 -1 0 1at 3639.843 kb on - strandat 3639.843 kb on - strandat 3640.265 kb on - strandat 3640.298 kb on - strandat 3640.530 kb on - strandat 3640.741 kb on + strand, within Rv3261at 3640.742 kb on - strand, within Rv3261at 3640.742 kb on - strand, within Rv3261at 3640.742 kb on - strand, within Rv3261at 3641.003 kb on + strand, within Rv3261at 3641.887 kb on + strand, within Rv3262at 3642.060 kb on + strand, within Rv3262at 3642.061 kb on - strand, within Rv3262at 3642.526 kb on + strand, within Rv3262

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5
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3,639,843 - +0.2
3,639,843 - -0.1
3,640,265 - +0.2
3,640,298 - -1.2
3,640,530 - -0.1
3,640,741 + Rv3261 0.20 -0.8
3,640,742 - Rv3261 0.20 -1.5
3,640,742 - Rv3261 0.20 -0.2
3,640,742 - Rv3261 0.20 -2.0
3,641,003 + Rv3261 0.46 +1.0
3,641,887 + Rv3262 0.26 -1.3
3,642,060 + Rv3262 0.39 -0.8
3,642,061 - Rv3262 0.39 -0.4
3,642,526 + Rv3262 0.74 -2.6

Or see this region's nucleotide sequence