Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2246

Experiment: 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

No fitness data for strains within 2,518,396 to 2,521,712
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500 ntRv2245 and Rv2246 are separated by 30 nucleotidesRv2246 and Rv2247 are separated by 30 nucleotides Rv2245: Rv2245 - 3-oxoacyl-[acyl-carrier protein] synthase 1 KasA (beta-ketoacyl-ACP synthase) (KAS I), at 2,518,115 to 2,519,365 Rv2245 Rv2246: Rv2246 - 3-oxoacyl-[acyl-carrier protein] synthase 2 KasB (beta-ketoacyl-ACP synthase) (KAS I), at 2,519,396 to 2,520,712 Rv2246 Rv2247: Rv2247 - Acetyl/propionyl-CoA carboxylase (beta subunit) AccD6, at 2,520,743 to 2,522,164 Rv2247