Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2191

Experiment: 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2190c and Rv2191 are separated by 546 nucleotidesRv2191 and Rv2192c overlap by 126 nucleotides Rv2190c: Rv2190c - Conserved hypothetical protein, at 2,452,115 to 2,453,272 Rv2190c Rv2191: Rv2191 - Conserved hypothetical protein, at 2,453,819 to 2,455,756 Rv2191 Rv2192c: Rv2192c - Probable anthranilate phosphoribosyltransferase TrpD, at 2,455,631 to 2,456,743 Rv2192c Position (kb) 2453 2454 2455 2456Strain fitness (log2 ratio) -2 -1 0 1 2at 2452.849 kb on + strand, within Rv2190cat 2452.928 kb on - strand, within Rv2190cat 2452.941 kb on + strand, within Rv2190cat 2452.942 kb on - strand, within Rv2190cat 2452.942 kb on - strand, within Rv2190cat 2452.942 kb on - strand, within Rv2190cat 2452.942 kb on - strand, within Rv2190cat 2453.286 kb on - strandat 2453.384 kb on + strandat 2453.416 kb on - strandat 2453.416 kb on - strandat 2453.424 kb on + strandat 2453.426 kb on + strandat 2453.427 kb on - strandat 2453.647 kb on + strandat 2453.647 kb on + strandat 2453.648 kb on - strandat 2453.686 kb on - strandat 2453.831 kb on - strandat 2454.039 kb on + strand, within Rv2191at 2454.040 kb on - strand, within Rv2191at 2454.079 kb on - strand, within Rv2191at 2454.146 kb on - strand, within Rv2191at 2454.268 kb on + strand, within Rv2191at 2454.343 kb on + strand, within Rv2191at 2454.344 kb on - strand, within Rv2191at 2454.482 kb on + strand, within Rv2191at 2454.482 kb on + strand, within Rv2191at 2454.483 kb on - strand, within Rv2191at 2454.483 kb on - strand, within Rv2191at 2454.500 kb on + strand, within Rv2191at 2454.501 kb on - strand, within Rv2191at 2454.575 kb on + strand, within Rv2191at 2454.575 kb on + strand, within Rv2191at 2454.575 kb on + strand, within Rv2191at 2454.575 kb on + strand, within Rv2191at 2454.575 kb on + strand, within Rv2191at 2454.576 kb on - strand, within Rv2191at 2454.608 kb on + strand, within Rv2191at 2454.608 kb on + strand, within Rv2191at 2454.609 kb on - strand, within Rv2191at 2454.642 kb on + strand, within Rv2191at 2454.650 kb on + strand, within Rv2191at 2454.650 kb on + strand, within Rv2191at 2454.651 kb on - strand, within Rv2191at 2454.651 kb on - strand, within Rv2191at 2454.651 kb on - strand, within Rv2191at 2454.789 kb on - strand, within Rv2191at 2455.172 kb on + strand, within Rv2191at 2455.173 kb on - strand, within Rv2191at 2455.308 kb on - strand, within Rv2191

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5
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2,452,849 + Rv2190c 0.63 +0.0
2,452,928 - Rv2190c 0.70 +1.5
2,452,941 + Rv2190c 0.71 -2.1
2,452,942 - Rv2190c 0.71 -2.0
2,452,942 - Rv2190c 0.71 -1.1
2,452,942 - Rv2190c 0.71 +1.1
2,452,942 - Rv2190c 0.71 -1.0
2,453,286 - -0.4
2,453,384 + -1.1
2,453,416 - +0.0
2,453,416 - -0.3
2,453,424 + +0.5
2,453,426 + +0.2
2,453,427 - -0.5
2,453,647 + -0.8
2,453,647 + +0.7
2,453,648 - -0.5
2,453,686 - -1.4
2,453,831 - -0.1
2,454,039 + Rv2191 0.11 -0.8
2,454,040 - Rv2191 0.11 -0.2
2,454,079 - Rv2191 0.13 -0.3
2,454,146 - Rv2191 0.17 +1.7
2,454,268 + Rv2191 0.23 +0.7
2,454,343 + Rv2191 0.27 -0.4
2,454,344 - Rv2191 0.27 -0.3
2,454,482 + Rv2191 0.34 -1.3
2,454,482 + Rv2191 0.34 +0.6
2,454,483 - Rv2191 0.34 +0.8
2,454,483 - Rv2191 0.34 +2.5
2,454,500 + Rv2191 0.35 -1.8
2,454,501 - Rv2191 0.35 +0.5
2,454,575 + Rv2191 0.39 -0.1
2,454,575 + Rv2191 0.39 +1.0
2,454,575 + Rv2191 0.39 -0.9
2,454,575 + Rv2191 0.39 +0.4
2,454,575 + Rv2191 0.39 -0.3
2,454,576 - Rv2191 0.39 -0.2
2,454,608 + Rv2191 0.41 +0.5
2,454,608 + Rv2191 0.41 +0.6
2,454,609 - Rv2191 0.41 -0.4
2,454,642 + Rv2191 0.42 -0.0
2,454,650 + Rv2191 0.43 -0.6
2,454,650 + Rv2191 0.43 +0.9
2,454,651 - Rv2191 0.43 -0.6
2,454,651 - Rv2191 0.43 +1.7
2,454,651 - Rv2191 0.43 -0.4
2,454,789 - Rv2191 0.50 +0.5
2,455,172 + Rv2191 0.70 -0.3
2,455,173 - Rv2191 0.70 +0.7
2,455,308 - Rv2191 0.77 -0.6

Or see this region's nucleotide sequence