Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2187

Experiment: 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Hydrogen peroxide 2.5 mM; pH 6.5
2,447,218	-		Rv2185c	0.35	+1.9
2,447,238	-		Rv2185c	0.40	+0.4
2,447,266	+		Rv2185c	0.46	-1.4
2,447,378	+		Rv2185c	0.72	+1.7
2,447,397	+		Rv2185c	0.76	+1.6
2,447,506	+				+3.5
2,447,507	-				-0.3
2,447,507	-				+1.7
2,447,578	+				-1.0
2,447,579	-				-0.2
2,447,606	+				+0.1
2,447,607	-				+0.2
2,448,010	+				-0.9
2,448,011	-				-0.6
2,448,099	+				+0.2
2,448,099	+				-0.1
2,448,262	+				+0.1
2,448,262	+				-0.5
2,448,262	+				+0.1
2,448,263	-				-0.1
2,448,263	-				-0.2
2,448,377	+		Rv2187	0.12	+0.7
2,448,378	-		Rv2187	0.12	+0.3
2,448,401	-		Rv2187	0.13	-0.4
2,448,452	+		Rv2187	0.16	+0.9
2,448,460	+		Rv2187	0.17	-0.5
2,448,461	-		Rv2187	0.17	+0.3
2,448,498	-		Rv2187	0.19	+0.1
2,448,498	-		Rv2187	0.19	+2.7
2,448,594	-		Rv2187	0.24	+0.1
2,448,594	-		Rv2187	0.24	-1.4
2,448,672	-		Rv2187	0.28	+1.3
2,448,693	-		Rv2187	0.30	+0.2
2,448,717	+		Rv2187	0.31	-0.1
2,448,718	-		Rv2187	0.31	+0.1
2,448,790	-		Rv2187	0.35	-0.2
2,448,886	-		Rv2187	0.40	+0.0
2,449,009	+		Rv2187	0.47	+0.8
2,449,010	-		Rv2187	0.47	-1.2
2,449,010	-		Rv2187	0.47	-0.6
2,449,163	-		Rv2187	0.56	+0.6
2,449,250	-		Rv2187	0.60	-0.3
2,449,273	+		Rv2187	0.62	+0.5
2,449,274	-		Rv2187	0.62	+0.1
2,449,376	+		Rv2187	0.67	-0.1
2,449,421	+		Rv2187	0.70	-3.2
2,449,422	-		Rv2187	0.70	-0.1
2,449,433	-		Rv2187	0.71	-0.2
2,449,948	+				-1.0
2,449,948	+				-0.4