Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2162c

Experiment: 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2160A and Rv2161c overlap by 8 nucleotidesRv2161c and Rv2162c are separated by 102 nucleotidesRv2162c and Rv2163c are separated by 209 nucleotides Rv2160A: Rv2160A - Conserved hypothetical protein, at 2,421,643 to 2,422,278 Rv2160A Rv2161c: Rv2161c - Conserved protein, at 2,422,271 to 2,423,137 Rv2161c Rv2162c: Rv2162c - PE-PGRS family protein PE_PGRS38, at 2,423,240 to 2,424,838 Rv2162c Rv2163c: Rv2163c - Probable penicillin-binding membrane protein PbpB, at 2,425,048 to 2,427,087 Rv2163c Position (kb) 2423 2424 2425Strain fitness (log2 ratio) -2 -1 0 1 2at 2422.447 kb on - strand, within Rv2161cat 2422.447 kb on - strand, within Rv2161cat 2422.680 kb on + strand, within Rv2161cat 2422.959 kb on + strand, within Rv2161cat 2422.960 kb on - strand, within Rv2161cat 2422.972 kb on - strand, within Rv2161cat 2423.043 kb on + strand, within Rv2161cat 2423.043 kb on + strand, within Rv2161cat 2423.043 kb on + strand, within Rv2161cat 2423.043 kb on + strand, within Rv2161cat 2423.043 kb on + strand, within Rv2161cat 2423.043 kb on + strand, within Rv2161cat 2423.043 kb on + strand, within Rv2161cat 2423.043 kb on + strand, within Rv2161cat 2423.044 kb on - strand, within Rv2161cat 2423.044 kb on - strand, within Rv2161cat 2423.044 kb on - strand, within Rv2161cat 2423.044 kb on - strand, within Rv2161cat 2423.044 kb on - strand, within Rv2161cat 2423.044 kb on - strand, within Rv2161cat 2423.044 kb on - strand, within Rv2161cat 2423.044 kb on - strand, within Rv2161cat 2423.154 kb on + strandat 2423.154 kb on + strandat 2423.155 kb on - strandat 2423.155 kb on - strandat 2423.155 kb on - strandat 2423.155 kb on - strandat 2423.390 kb on - strandat 2423.670 kb on + strand, within Rv2162cat 2423.670 kb on + strand, within Rv2162cat 2423.671 kb on - strand, within Rv2162cat 2424.285 kb on + strand, within Rv2162cat 2424.286 kb on - strand, within Rv2162cat 2424.422 kb on - strand, within Rv2162cat 2424.435 kb on + strand, within Rv2162cat 2424.625 kb on - strand, within Rv2162cat 2424.655 kb on - strand, within Rv2162cat 2424.655 kb on - strand, within Rv2162cat 2424.913 kb on + strandat 2425.050 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5
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2,422,447 - Rv2161c 0.20 -0.0
2,422,447 - Rv2161c 0.20 -0.2
2,422,680 + Rv2161c 0.47 +0.7
2,422,959 + Rv2161c 0.79 -0.3
2,422,960 - Rv2161c 0.79 -2.1
2,422,972 - Rv2161c 0.81 +0.4
2,423,043 + Rv2161c 0.89 +0.7
2,423,043 + Rv2161c 0.89 +0.6
2,423,043 + Rv2161c 0.89 +0.3
2,423,043 + Rv2161c 0.89 -0.2
2,423,043 + Rv2161c 0.89 -1.4
2,423,043 + Rv2161c 0.89 -0.6
2,423,043 + Rv2161c 0.89 +0.1
2,423,043 + Rv2161c 0.89 -0.5
2,423,044 - Rv2161c 0.89 -0.4
2,423,044 - Rv2161c 0.89 +0.6
2,423,044 - Rv2161c 0.89 -0.2
2,423,044 - Rv2161c 0.89 +1.4
2,423,044 - Rv2161c 0.89 +2.0
2,423,044 - Rv2161c 0.89 +0.1
2,423,044 - Rv2161c 0.89 -0.6
2,423,044 - Rv2161c 0.89 +0.4
2,423,154 + +0.0
2,423,154 + +0.7
2,423,155 - +0.7
2,423,155 - -0.5
2,423,155 - -0.3
2,423,155 - -1.0
2,423,390 - +0.1
2,423,670 + Rv2162c 0.27 +0.2
2,423,670 + Rv2162c 0.27 +0.7
2,423,671 - Rv2162c 0.27 +0.5
2,424,285 + Rv2162c 0.65 -1.4
2,424,286 - Rv2162c 0.65 +0.1
2,424,422 - Rv2162c 0.74 +1.7
2,424,435 + Rv2162c 0.75 +0.5
2,424,625 - Rv2162c 0.87 +0.5
2,424,655 - Rv2162c 0.88 -0.2
2,424,655 - Rv2162c 0.88 +0.2
2,424,913 + -0.0
2,425,050 - -0.3

Or see this region's nucleotide sequence