Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1780

Experiment: 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1779c and Rv1780 are separated by 219 nucleotidesRv1780 and Rv1781c are separated by 39 nucleotides Rv1779c: Rv1779c - Possible integral membrane protein, at 2,012,686 to 2,014,479 Rv1779c Rv1780: Rv1780 - Conserved protein, at 2,014,699 to 2,015,262 Rv1780 Rv1781c: Rv1781c - Probable 4-alpha-glucanotransferase MalQ (amylomaltase) (disproportionating enzyme) (D-enzyme), at 2,015,302 to 2,017,476 Rv1781c Position (kb) 2014 2015 2016Strain fitness (log2 ratio) -4 -3 -2 -1 0 1 2at 2014.059 kb on + strand, within Rv1779cat 2014.059 kb on + strand, within Rv1779cat 2014.060 kb on - strand, within Rv1779cat 2014.060 kb on - strand, within Rv1779cat 2014.419 kb on + strandat 2014.419 kb on + strandat 2014.420 kb on - strandat 2014.420 kb on - strandat 2014.420 kb on - strandat 2014.464 kb on - strandat 2014.690 kb on + strandat 2014.691 kb on - strandat 2014.691 kb on - strandat 2014.692 kb on + strandat 2014.692 kb on + strandat 2014.692 kb on + strandat 2014.692 kb on + strandat 2014.693 kb on - strandat 2014.693 kb on - strandat 2014.698 kb on + strandat 2014.698 kb on + strandat 2014.698 kb on + strandat 2014.698 kb on + strandat 2014.699 kb on - strandat 2014.720 kb on - strandat 2014.762 kb on - strand, within Rv1780at 2014.762 kb on - strand, within Rv1780at 2015.039 kb on + strand, within Rv1780at 2015.040 kb on - strand, within Rv1780at 2015.074 kb on + strand, within Rv1780at 2015.170 kb on + strand, within Rv1780at 2015.170 kb on + strand, within Rv1780at 2015.171 kb on - strand, within Rv1780at 2015.244 kb on + strandat 2015.245 kb on - strandat 2015.535 kb on - strand, within Rv1781cat 2015.535 kb on - strand, within Rv1781cat 2015.540 kb on + strand, within Rv1781cat 2015.672 kb on - strand, within Rv1781cat 2015.699 kb on - strand, within Rv1781cat 2015.699 kb on - strand, within Rv1781cat 2015.718 kb on - strand, within Rv1781cat 2015.718 kb on - strand, within Rv1781cat 2015.863 kb on + strand, within Rv1781cat 2015.864 kb on - strand, within Rv1781cat 2015.864 kb on - strand, within Rv1781cat 2015.866 kb on + strand, within Rv1781cat 2015.866 kb on + strand, within Rv1781cat 2015.870 kb on + strand, within Rv1781cat 2015.870 kb on + strand, within Rv1781cat 2015.871 kb on - strand, within Rv1781cat 2015.871 kb on - strand, within Rv1781cat 2015.984 kb on + strand, within Rv1781cat 2015.984 kb on + strand, within Rv1781cat 2015.984 kb on + strand, within Rv1781cat 2015.984 kb on + strand, within Rv1781cat 2015.984 kb on + strand, within Rv1781cat 2015.984 kb on + strand, within Rv1781cat 2015.985 kb on - strand, within Rv1781cat 2015.985 kb on - strand, within Rv1781cat 2015.985 kb on - strand, within Rv1781cat 2015.985 kb on - strand, within Rv1781cat 2015.985 kb on - strand, within Rv1781cat 2015.985 kb on - strand, within Rv1781cat 2015.985 kb on - strand, within Rv1781cat 2015.985 kb on - strand, within Rv1781cat 2015.985 kb on - strand, within Rv1781cat 2016.110 kb on + strand, within Rv1781c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5
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2,014,059 + Rv1779c 0.77 -0.5
2,014,059 + Rv1779c 0.77 -1.3
2,014,060 - Rv1779c 0.77 -0.6
2,014,060 - Rv1779c 0.77 -0.2
2,014,419 + -0.1
2,014,419 + -0.5
2,014,420 - +1.7
2,014,420 - -0.1
2,014,420 - -0.8
2,014,464 - -0.2
2,014,690 + -1.1
2,014,691 - +0.5
2,014,691 - -0.3
2,014,692 + -0.2
2,014,692 + +0.2
2,014,692 + +0.5
2,014,692 + -0.3
2,014,693 - -3.8
2,014,693 - +0.3
2,014,698 + +2.5
2,014,698 + -0.9
2,014,698 + -1.2
2,014,698 + -0.6
2,014,699 - -1.3
2,014,720 - +0.5
2,014,762 - Rv1780 0.11 -1.1
2,014,762 - Rv1780 0.11 -1.3
2,015,039 + Rv1780 0.60 -2.1
2,015,040 - Rv1780 0.60 -1.8
2,015,074 + Rv1780 0.66 -1.3
2,015,170 + Rv1780 0.84 -0.6
2,015,170 + Rv1780 0.84 +0.5
2,015,171 - Rv1780 0.84 +0.3
2,015,244 + +0.2
2,015,245 - +0.0
2,015,535 - Rv1781c 0.11 -0.4
2,015,535 - Rv1781c 0.11 -0.8
2,015,540 + Rv1781c 0.11 -0.7
2,015,672 - Rv1781c 0.17 +0.3
2,015,699 - Rv1781c 0.18 -0.0
2,015,699 - Rv1781c 0.18 -1.1
2,015,718 - Rv1781c 0.19 +0.2
2,015,718 - Rv1781c 0.19 -1.1
2,015,863 + Rv1781c 0.26 -0.8
2,015,864 - Rv1781c 0.26 +0.1
2,015,864 - Rv1781c 0.26 -0.3
2,015,866 + Rv1781c 0.26 -0.9
2,015,866 + Rv1781c 0.26 -0.2
2,015,870 + Rv1781c 0.26 +0.1
2,015,870 + Rv1781c 0.26 -1.3
2,015,871 - Rv1781c 0.26 -0.0
2,015,871 - Rv1781c 0.26 -0.6
2,015,984 + Rv1781c 0.31 +1.7
2,015,984 + Rv1781c 0.31 -0.7
2,015,984 + Rv1781c 0.31 -0.5
2,015,984 + Rv1781c 0.31 -0.0
2,015,984 + Rv1781c 0.31 -0.3
2,015,984 + Rv1781c 0.31 +1.7
2,015,985 - Rv1781c 0.31 +0.1
2,015,985 - Rv1781c 0.31 +0.2
2,015,985 - Rv1781c 0.31 -0.7
2,015,985 - Rv1781c 0.31 +0.2
2,015,985 - Rv1781c 0.31 -0.4
2,015,985 - Rv1781c 0.31 -0.3
2,015,985 - Rv1781c 0.31 +2.1
2,015,985 - Rv1781c 0.31 -0.5
2,015,985 - Rv1781c 0.31 -0.4
2,016,110 + Rv1781c 0.37 -0.3

Or see this region's nucleotide sequence