Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1688

Experiment: 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1686c and Rv1687c are separated by 71 nucleotidesRv1687c and Rv1688 are separated by 58 nucleotidesRv1688 and Rv1689 are separated by 11 nucleotides Rv1686c: Rv1686c - Probable conserved integral membrane protein ABC transporter, at 1,911,401 to 1,912,081 Rv1686c Rv1687c: Rv1687c - Probable conserved ATP-binding protein ABC transporter, at 1,912,153 to 1,912,920 Rv1687c Rv1688: Rv1688 - Possible 3-methyladenine DNA glycosylase Mpg, at 1,912,979 to 1,913,590 Rv1688 Rv1689: Rv1689 - Probable tyrosyl-tRNA synthase TyrS (TYRRS), at 1,913,602 to 1,914,876 Rv1689 Position (kb) 1912 1913 1914Strain fitness (log2 ratio) -1 0 1at 1912.041 kb on + strandat 1912.042 kb on - strandat 1912.140 kb on + strandat 1912.140 kb on + strandat 1912.141 kb on - strandat 1912.238 kb on - strand, within Rv1687cat 1912.319 kb on - strand, within Rv1687cat 1912.590 kb on - strand, within Rv1687cat 1912.646 kb on + strand, within Rv1687cat 1912.646 kb on + strand, within Rv1687cat 1912.647 kb on - strand, within Rv1687cat 1913.041 kb on + strand, within Rv1688at 1913.042 kb on - strand, within Rv1688at 1913.088 kb on - strand, within Rv1688at 1913.088 kb on - strand, within Rv1688at 1913.189 kb on + strand, within Rv1688at 1913.190 kb on - strand, within Rv1688at 1913.265 kb on + strand, within Rv1688

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5
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1,912,041 + +0.0
1,912,042 - +0.3
1,912,140 + +0.0
1,912,140 + +1.4
1,912,141 - -0.4
1,912,238 - Rv1687c 0.11 +0.3
1,912,319 - Rv1687c 0.22 +1.1
1,912,590 - Rv1687c 0.57 -0.5
1,912,646 + Rv1687c 0.64 +0.3
1,912,646 + Rv1687c 0.64 -0.7
1,912,647 - Rv1687c 0.64 -0.1
1,913,041 + Rv1688 0.10 +0.4
1,913,042 - Rv1688 0.10 +0.4
1,913,088 - Rv1688 0.18 -1.5
1,913,088 - Rv1688 0.18 -1.1
1,913,189 + Rv1688 0.34 -0.7
1,913,190 - Rv1688 0.34 -0.4
1,913,265 + Rv1688 0.47 -0.8

Or see this region's nucleotide sequence