Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1682

Experiment: 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1681 and Rv1682 are separated by 160 nucleotidesRv1682 and Rv1683 are separated by 273 nucleotides Rv1681: Rv1681 - Possible molybdopterin biosynthesis protein MoeX, at 1,905,250 to 1,906,242 Rv1681 Rv1682: Rv1682 - Probable coiled-coil structural protein, at 1,906,403 to 1,907,320 Rv1682 Rv1683: Rv1683 - Possible bifunctional enzyme; long-chain acyl-CoA synthase and lipase., at 1,907,594 to 1,910,593 Rv1683 Position (kb) 1906 1907 1908Strain fitness (log2 ratio) -3 -2 -1 0 1 2 3at 1905.771 kb on + strand, within Rv1681at 1905.771 kb on + strand, within Rv1681at 1905.772 kb on - strand, within Rv1681at 1905.772 kb on - strand, within Rv1681at 1905.860 kb on + strand, within Rv1681at 1905.861 kb on - strand, within Rv1681at 1905.861 kb on - strand, within Rv1681at 1906.094 kb on - strand, within Rv1681at 1906.175 kb on + strandat 1906.175 kb on + strandat 1906.176 kb on - strandat 1906.176 kb on - strandat 1906.176 kb on - strandat 1906.240 kb on + strandat 1906.240 kb on + strandat 1906.241 kb on - strandat 1906.309 kb on - strandat 1906.466 kb on + strandat 1906.466 kb on + strandat 1906.467 kb on - strandat 1906.550 kb on + strand, within Rv1682at 1906.618 kb on - strand, within Rv1682at 1906.764 kb on + strand, within Rv1682at 1906.765 kb on - strand, within Rv1682at 1906.765 kb on - strand, within Rv1682at 1906.829 kb on - strand, within Rv1682at 1907.230 kb on + strandat 1907.286 kb on + strandat 1907.319 kb on - strandat 1907.571 kb on + strandat 1908.062 kb on + strand, within Rv1683

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5
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1,905,771 + Rv1681 0.52 -0.9
1,905,771 + Rv1681 0.52 -0.5
1,905,772 - Rv1681 0.53 +1.7
1,905,772 - Rv1681 0.53 +0.0
1,905,860 + Rv1681 0.61 -0.0
1,905,861 - Rv1681 0.62 -1.1
1,905,861 - Rv1681 0.62 +0.9
1,906,094 - Rv1681 0.85 +3.3
1,906,175 + -0.1
1,906,175 + -0.7
1,906,176 - -3.1
1,906,176 - -1.3
1,906,176 - +0.9
1,906,240 + -0.5
1,906,240 + -0.6
1,906,241 - +1.7
1,906,309 - -0.8
1,906,466 + +1.7
1,906,466 + +0.4
1,906,467 - +0.2
1,906,550 + Rv1682 0.16 -0.4
1,906,618 - Rv1682 0.23 +1.7
1,906,764 + Rv1682 0.39 +0.0
1,906,765 - Rv1682 0.39 -2.1
1,906,765 - Rv1682 0.39 -1.0
1,906,829 - Rv1682 0.46 -0.3
1,907,230 + +1.7
1,907,286 + +1.4
1,907,319 - -2.4
1,907,571 + +0.3
1,908,062 + Rv1683 0.16 -0.6

Or see this region's nucleotide sequence