Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1264

Experiment: 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1263 and Rv1264 are separated by 74 nucleotidesRv1264 and Rv1265 are separated by 172 nucleotidesRv1265 and Rv1266c are separated by 19 nucleotides Rv1263: Rv1263 - Probable amidase AmiB2 (aminohydrolase), at 1,410,431 to 1,411,819 Rv1263 Rv1264: Rv1264 - Adenylyl cyclase (ATP pyrophosphate-lyase) (adenylate cyclase), at 1,411,894 to 1,413,087 Rv1264 Rv1265: Rv1265 - Unknown protein, at 1,413,260 to 1,413,940 Rv1265 Rv1266c: Rv1266c - Probable transmembrane serine/threonine-protein kinase H PknH (protein kinase H) (STPK H), at 1,413,960 to 1,415,840 Rv1266c Position (kb) 1411 1412 1413 1414Strain fitness (log2 ratio) -2 -1 0 1at 1411.278 kb on + strand, within Rv1263at 1411.334 kb on + strand, within Rv1263at 1411.335 kb on - strand, within Rv1263at 1411.343 kb on + strand, within Rv1263at 1411.344 kb on - strand, within Rv1263at 1411.437 kb on + strand, within Rv1263at 1411.533 kb on + strand, within Rv1263at 1411.533 kb on + strand, within Rv1263at 1411.634 kb on + strand, within Rv1263at 1411.635 kb on - strand, within Rv1263at 1412.089 kb on + strand, within Rv1264at 1412.089 kb on + strand, within Rv1264at 1412.089 kb on + strand, within Rv1264at 1412.090 kb on - strand, within Rv1264at 1412.090 kb on - strand, within Rv1264at 1412.090 kb on - strand, within Rv1264at 1412.090 kb on - strand, within Rv1264at 1412.090 kb on - strand, within Rv1264at 1412.094 kb on - strand, within Rv1264at 1412.119 kb on + strand, within Rv1264at 1412.119 kb on + strand, within Rv1264at 1412.120 kb on - strand, within Rv1264at 1412.673 kb on + strand, within Rv1264at 1412.674 kb on - strand, within Rv1264at 1413.085 kb on + strandat 1413.085 kb on + strandat 1413.237 kb on - strandat 1413.237 kb on - strandat 1413.401 kb on + strand, within Rv1265

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5
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1,411,278 + Rv1263 0.61 +0.1
1,411,334 + Rv1263 0.65 -0.1
1,411,335 - Rv1263 0.65 +1.7
1,411,343 + Rv1263 0.66 +0.1
1,411,344 - Rv1263 0.66 +0.2
1,411,437 + Rv1263 0.72 -0.6
1,411,533 + Rv1263 0.79 -0.0
1,411,533 + Rv1263 0.79 +0.1
1,411,634 + Rv1263 0.87 +0.7
1,411,635 - Rv1263 0.87 -0.6
1,412,089 + Rv1264 0.16 -2.0
1,412,089 + Rv1264 0.16 -0.4
1,412,089 + Rv1264 0.16 -1.2
1,412,090 - Rv1264 0.16 +0.0
1,412,090 - Rv1264 0.16 -0.3
1,412,090 - Rv1264 0.16 -0.5
1,412,090 - Rv1264 0.16 -0.6
1,412,090 - Rv1264 0.16 -1.2
1,412,094 - Rv1264 0.17 +0.2
1,412,119 + Rv1264 0.19 -0.5
1,412,119 + Rv1264 0.19 -0.0
1,412,120 - Rv1264 0.19 -0.3
1,412,673 + Rv1264 0.65 -0.3
1,412,674 - Rv1264 0.65 -2.0
1,413,085 + -1.3
1,413,085 + +0.5
1,413,237 - -0.5
1,413,237 - -0.5
1,413,401 + Rv1265 0.21 +1.3

Or see this region's nucleotide sequence