Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1230c

Experiment: 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1229c and Rv1230c are separated by 12 nucleotidesRv1230c and Rv1231c are separated by 124 nucleotidesRv1231c and Rv1232c overlap by 4 nucleotides Rv1229c: Rv1229c - Probable Mrp-related protein Mrp, at 1,371,777 to 1,372,949 Rv1229c Rv1230c: Rv1230c - Possible membrane protein, at 1,372,962 to 1,374,197 Rv1230c Rv1231c: Rv1231c - Probable membrane protein, at 1,374,322 to 1,374,864 Rv1231c Rv1232c: Rv1232c - Conserved protein, at 1,374,861 to 1,376,168 Rv1232c Position (kb) 1372 1373 1374 1375Strain fitness (log2 ratio) -3 -2 -1 0 1 2at 1372.935 kb on + strandat 1372.936 kb on - strandat 1372.950 kb on - strandat 1373.050 kb on - strandat 1373.398 kb on - strand, within Rv1230cat 1373.410 kb on + strand, within Rv1230cat 1373.566 kb on + strand, within Rv1230cat 1373.567 kb on - strand, within Rv1230cat 1373.617 kb on + strand, within Rv1230cat 1373.692 kb on + strand, within Rv1230cat 1373.915 kb on + strand, within Rv1230cat 1373.916 kb on - strand, within Rv1230cat 1373.916 kb on - strand, within Rv1230cat 1373.983 kb on - strand, within Rv1230cat 1374.232 kb on + strandat 1374.233 kb on - strandat 1374.233 kb on - strandat 1374.233 kb on - strandat 1374.243 kb on - strandat 1374.267 kb on + strandat 1374.267 kb on + strandat 1374.278 kb on - strandat 1374.444 kb on - strand, within Rv1231cat 1374.503 kb on + strand, within Rv1231cat 1374.503 kb on + strand, within Rv1231cat 1374.503 kb on + strand, within Rv1231cat 1374.504 kb on - strand, within Rv1231cat 1374.611 kb on + strand, within Rv1231cat 1374.709 kb on + strand, within Rv1231cat 1374.709 kb on + strand, within Rv1231cat 1374.734 kb on + strand, within Rv1231cat 1374.833 kb on + strandat 1374.833 kb on + strandat 1374.914 kb on + strandat 1374.914 kb on + strandat 1374.939 kb on + strandat 1374.939 kb on + strandat 1374.939 kb on + strandat 1374.939 kb on + strandat 1374.939 kb on + strandat 1374.939 kb on + strandat 1374.940 kb on - strandat 1375.033 kb on + strand, within Rv1232c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5
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1,372,935 + -0.0
1,372,936 - -0.7
1,372,950 - -0.6
1,373,050 - -0.0
1,373,398 - Rv1230c 0.35 +0.1
1,373,410 + Rv1230c 0.36 -0.7
1,373,566 + Rv1230c 0.49 +0.3
1,373,567 - Rv1230c 0.49 +0.3
1,373,617 + Rv1230c 0.53 +1.0
1,373,692 + Rv1230c 0.59 +0.6
1,373,915 + Rv1230c 0.77 +0.6
1,373,916 - Rv1230c 0.77 +0.1
1,373,916 - Rv1230c 0.77 +0.3
1,373,983 - Rv1230c 0.83 -0.0
1,374,232 + +0.2
1,374,233 - +0.7
1,374,233 - -1.0
1,374,233 - +2.2
1,374,243 - -0.9
1,374,267 + -2.7
1,374,267 + +0.5
1,374,278 - -0.5
1,374,444 - Rv1231c 0.22 -0.4
1,374,503 + Rv1231c 0.33 -0.8
1,374,503 + Rv1231c 0.33 -0.7
1,374,503 + Rv1231c 0.33 -2.9
1,374,504 - Rv1231c 0.34 +0.7
1,374,611 + Rv1231c 0.53 -2.2
1,374,709 + Rv1231c 0.71 -1.1
1,374,709 + Rv1231c 0.71 -0.2
1,374,734 + Rv1231c 0.76 +0.1
1,374,833 + -0.5
1,374,833 + -0.1
1,374,914 + -1.3
1,374,914 + +0.3
1,374,939 + +0.9
1,374,939 + -0.9
1,374,939 + -0.5
1,374,939 + +0.4
1,374,939 + -1.1
1,374,939 + -0.1
1,374,940 - -0.6
1,375,033 + Rv1232c 0.13 +0.4

Or see this region's nucleotide sequence