Experiment: 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv1159 and Rv1159A overlap by 4 nucleotides Rv1159A and Rv1160 are separated by 26 nucleotides Rv1160 and Rv1161 are separated by 307 nucleotides
Rv1159: Rv1159 - Mannosyltransferase PimE, at 1,284,992 to 1,286,287
Rv1159
Rv1159A: Rv1159A - Unknown protein, at 1,286,284 to 1,286,568
Rv1159A
Rv1160: Rv1160 - Probable mutator protein MutT2 (7,8-dihydro-8-oxoguanine-triphosphatase) (8-oxo-dGTPase), at 1,286,595 to 1,287,020
Rv1160
Rv1161: Rv1161 - Respiratory nitrate reductase (alpha chain) NarG, at 1,287,328 to 1,291,026
Rv1161
Position (kb)
1286
1287
1288 Strain fitness (log2 ratio)
-2
-1
0
1
2 at 1285.754 kb on + strand, within Rv1159 at 1285.902 kb on + strand, within Rv1159 at 1286.252 kb on + strand at 1286.252 kb on + strand at 1286.253 kb on - strand at 1286.253 kb on - strand at 1286.285 kb on + strand at 1286.285 kb on + strand at 1286.413 kb on + strand, within Rv1159A at 1286.413 kb on + strand, within Rv1159A at 1286.558 kb on - strand at 1286.568 kb on + strand at 1286.569 kb on - strand at 1286.579 kb on + strand at 1286.581 kb on + strand at 1286.848 kb on - strand, within Rv1160 at 1286.941 kb on + strand, within Rv1160 at 1287.112 kb on + strand at 1287.464 kb on - strand at 1287.544 kb on + strand at 1287.619 kb on + strand at 1287.619 kb on + strand at 1287.667 kb on + strand at 1287.668 kb on - strand at 1287.695 kb on - strand at 1287.722 kb on - strand, within Rv1161 at 1287.722 kb on - strand, within Rv1161 at 1287.898 kb on + strand, within Rv1161 at 1287.899 kb on - strand, within Rv1161 at 1288.009 kb on + strand, within Rv1161 at 1288.019 kb on - strand, within Rv1161
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5 remove 1,285,754 + Rv1159 0.59 -0.5 1,285,902 + Rv1159 0.70 -1.1 1,286,252 + +0.3 1,286,252 + -0.2 1,286,253 - -0.4 1,286,253 - -0.9 1,286,285 + +2.1 1,286,285 + -0.0 1,286,413 + Rv1159A 0.45 -0.4 1,286,413 + Rv1159A 0.45 -1.1 1,286,558 - -0.5 1,286,568 + -0.4 1,286,569 - -0.2 1,286,579 + -0.1 1,286,581 + +0.1 1,286,848 - Rv1160 0.59 +1.1 1,286,941 + Rv1160 0.81 +2.4 1,287,112 + +0.3 1,287,464 - +0.3 1,287,544 + +1.7 1,287,619 + -0.6 1,287,619 + +0.5 1,287,667 + -0.1 1,287,668 - +0.5 1,287,695 - -1.4 1,287,722 - Rv1161 0.11 -1.6 1,287,722 - Rv1161 0.11 -2.2 1,287,898 + Rv1161 0.15 +0.2 1,287,899 - Rv1161 0.15 +0.1 1,288,009 + Rv1161 0.18 -0.6 1,288,019 - Rv1161 0.19 -0.1
Or see this region's nucleotide sequence