Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1149

Experiment: 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1148c and Rv1149 are separated by 144 nucleotidesRv1149 and Rv1150 overlap by 32 nucleotidesRv1150 and Rv1151c are separated by 83 nucleotides Rv1148c: Rv1148c - Conserved hypothetical protein, at 1,276,300 to 1,277,748 Rv1148c Rv1149: Rv1149 - Possible transposase, at 1,277,893 to 1,278,300 Rv1149 Rv1150: Rv1150 - Possible transposase (fragment), at 1,278,269 to 1,278,820 Rv1150 Rv1151c: Rv1151c - Transcriptional regulatory protein, at 1,278,904 to 1,279,617 Rv1151c Position (kb) 1277 1278 1279Strain fitness (log2 ratio) -1 0 1at 1277.709 kb on + strandat 1277.826 kb on + strandat 1277.845 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5
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1,277,709 + +0.0
1,277,826 + -0.8
1,277,845 - +0.5

Or see this region's nucleotide sequence