Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1097c

Experiment: 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1095 and Rv1096 are separated by 86 nucleotidesRv1096 and Rv1097c are separated by 2 nucleotidesRv1097c and Rv1098c overlap by 4 nucleotides Rv1095: Rv1095 - Probable PHOH-like protein PhoH2 (phosphate starvation-inducible protein PSIH), at 1,222,997 to 1,224,298 Rv1095 Rv1096: Rv1096 - Possible glycosyl hydrolase, at 1,224,385 to 1,225,260 Rv1096 Rv1097c: Rv1097c - Probable membrane glycine and proline rich protein, at 1,225,263 to 1,226,144 Rv1097c Rv1098c: Rv1098c - Probable fumarase Fum (fumarate hydratase), at 1,226,141 to 1,227,565 Rv1098c Position (kb) 1225 1226 1227Strain fitness (log2 ratio) -1 0 1at 1224.714 kb on + strand, within Rv1096at 1225.100 kb on - strand, within Rv1096at 1225.259 kb on - strandat 1225.431 kb on - strand, within Rv1097cat 1225.517 kb on - strand, within Rv1097cat 1225.734 kb on - strand, within Rv1097cat 1226.111 kb on - strandat 1226.111 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5
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1,224,714 + Rv1096 0.38 +0.9
1,225,100 - Rv1096 0.82 +0.7
1,225,259 - +0.7
1,225,431 - Rv1097c 0.19 +0.7
1,225,517 - Rv1097c 0.29 +0.5
1,225,734 - Rv1097c 0.53 +1.7
1,226,111 - +1.7
1,226,111 - +0.1

Or see this region's nucleotide sequence